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• W179960110 abstract "Nucleotide-binding and leucine rich repeat domain-containing proteins (NLRs) are central to the formation of many inflammasome complexes. Several inflammasome forming NLR proteins are known to be ATPases, but the nucleotide binding specificity of many remains to be characterized. The oligomerization of NLR proteins and assembly of inflammasomes require the ATP (or other nucleotide) binding activity of the NLR proteins. Quantitative and qualitative studies of the nucleotide binding properties of these proteins are useful tools in studying the regulation of inflammasome activity, and are outlined in this Chapter." @default.
• W179960110 created "2016-06-24" @default.
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• W179960110 date "2013-01-01" @default.
• W179960110 modified "2023-10-07" @default.
• W179960110 title "Assessing ATP Binding and Hydrolysis by NLR Proteins" @default.
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• W179960110 doi "https://doi.org/10.1007/978-1-62703-523-1_12" @default.
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