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• W179965839 abstract "Overlap exists between several functional somatic illnesses like chronic fatigue syndrome (CFS), multiple chemical sensitivity and myalgic encephalomyelitis (ME). Recently, researchers suggested that these entities are due to similar mechanisms with possible differences in symptom clusters. For instance, post-exertional malaise and impairment of memory and attention are essential for the ME but are not required in the CFS although symptom clusters only differ in severity. This study compares 26 ME patients and 41 CFS patients regarding cognitive problems and functionality using standardized objective test batteries instead of self-reported measures. Should no distinct features emerge, then ME could merge in the continuum CFS. No differences were found regarding functional status although ME patients reported more general fatigue. ME patients have more attention problems whereas CFS patients show more memory difficulties and a slower reaction time. Our results do not fully support the research for ME. These differences could be more helpful in delineating a continuum instead of supporting distinct conditions. Chronic fatigue syndrome (CFS) still evokes controversy in the medical literature. There may be several reasons for this. First, many different case definitions create heterogeneity not amenable to meta-analysis (Van Hoof et al., 2003). Second, clinicians become entangled because of the different possible ways to define its context. For instance, in the International Classification of Diseases (ICD-10), CFS is classified as a neurological condition (G93.3) but when using the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV), CFS is called undifferentiated somatoform disorder or neurasthenia (F48.0). Finally, overlapping diagnoses occur among many conditions including CFS, Fibromyalgia, multiple chemical sensitivity, myalgic encephalomyelitis (ME), rheumatoid arthritis, and irritable bowel syndrome. This overlap suggest that these 'functional somatic illnesses' may be variants of one another. Several researchers have already suggested that these entities are due to similar if not identical mechanisms (Bruno et al., 1998; Buchwald et al., 1994; Donnay & Ziem, 1999; Hudson et al., 1992; Miller, 1999). The different conditions are thought to vary in the severity and the chronicity of complaints, producing distinct entities. According to the 1994 CFS criteria, a patient is required to experience chronic fatigue of a new or definite onset (for 6 or more months) that is not substantially alleviated by rest, is not the result of ongoing exertion, and produces significant reductions in occupational, social or personal activities. The Fukuda et al. (Fukuda et al., 1994) also require the concurrent presence of at least 4 of 8 other symptoms: Self-reported persistent or recurrent impairment in short-term memory or concentration resulting in previous levels of occupational, educational, social, or personal activities; sore throat; tender cervical or axillary lymph nodes; muscle pain; multiple joint pain; headaches of a new type, pattern, or severity; unrefreshing sleep; and post exertional malaise lasting more than 24 hours. Conversely, many patients, especially in Britain, prefer the term myalgic encephalomyelitis (ME) rather than the term CFS. The term ME refers to an underlying medical cause. Subsequently, the stigma associated with CFS is not present. The include (a) fatigue after minimal exertion (not daily fatigue) and delay of recovery of muscle power after exertion and, (b) 1 or more symptoms that indicate circulatory impairment, (c) 1 or more symptoms that indicate central nervous system involvement (cerebral problems), and (d) fluctuating symptoms (Ramsay, 1981; Ramsay, 1988). In 1992, Goudsmit and colleagues developed the criteria for research on ME. The London include (a) exercise-induced fatigue caused by small amounts of exertion (physical or mental) compared to previously tolerated levels, (b) neurological disturbances, especially impaired memory and concentration, (c) fluctuation of symptoms, and (d) the requirement for the ongoing presence of these symptoms for at least 6 months (National Task Force, 1994). …" @default.
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• W179965839 date "2005-06-01" @default.
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• W179965839 title "Chronic Fatigue syndrome and myalgic encephalomyelitis: Are both conditions on the same continuum?" @default.
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