FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1799665930> ?p ?o ?g. }

• W1799665930 endingPage "444" @default.
• W1799665930 startingPage "436" @default.
• W1799665930 abstract "Abstract: Melatonin reportedly exerts beneficial effects to attenuate multiple organ dysfunction syndrome (MODS) in septic shock. Heatstroke resembles septic shock in many aspects. Thus, this study was performed on the anesthetized rats by using heat exposure to induce heatstroke‐associated MODS. We evaluated the effect of melatonin, a versatile molecule synthesized in the pineal gland and in many organs, in heatstroke rats and showed that melatonin (0.2–5.0 mg/kg of body weight, i.v., immediately after the start of heat stress) significantly (i) attenuated hyperthermia, hypotension and hypothalamic ischemia and hypoxia, (ii) reduced plasma index of the toxic oxidizing radicals like nitric oxide metabolites and hydroxyl radicals, (iii) diminished plasma index of hepatic and renal dysfunction like creatinine, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and lactate dehydrogenase, (iv) attenuated plasma systemic inflammation response molecules like soluble intercellular and lesion molecule‐1, E‐selectin, tumor necrosis factor‐alpha, interleukin (IL)‐1β, and IL‐6, (v) promoted plasma levels of an anti‐inflammatory cytokine IL‐10, (vi) reduced an index of infiltration of polymorphonuclear neutrophils in the lung like myeloperoxidase activity, and (vii) promoted the survival time to fourfold compared with the heatstroke alone group. Thus, melatonin could be a novel agent for the treatment of heatstroke animals or patients in the early stage." @default.
• W1799665930 created "2016-06-24" @default.
• W1799665930 creator A5008231346 @default.
• W1799665930 creator A5024257143 @default.
• W1799665930 creator A5050487933 @default.
• W1799665930 creator A5051082508 @default.
• W1799665930 creator A5060165452 @default.
• W1799665930 creator A5072439406 @default.
• W1799665930 creator A5076408469 @default.
• W1799665930 creator A5083830540 @default.
• W1799665930 date "2011-03-11" @default.
• W1799665930 modified "2023-10-17" @default.
• W1799665930 title "Therapeutic effects of melatonin on heatstroke-induced multiple organ dysfunction syndrome in rats" @default.
• W1799665930 cites W1494575416 @default.
• W1799665930 cites W1858048769 @default.
• W1799665930 cites W1900762885 @default.
• W1799665930 cites W1970552378 @default.
• W1799665930 cites W1983428930 @default.
• W1799665930 cites W1984328377 @default.
• W1799665930 cites W1988934115 @default.
• W1799665930 cites W1990845992 @default.
• W1799665930 cites W2006761570 @default.
• W1799665930 cites W2018489283 @default.
• W1799665930 cites W2023119268 @default.
• W1799665930 cites W2023700147 @default.
• W1799665930 cites W2032517215 @default.
• W1799665930 cites W2045993202 @default.
• W1799665930 cites W2049561891 @default.
• W1799665930 cites W2050585388 @default.
• W1799665930 cites W2059829735 @default.
• W1799665930 cites W2060395881 @default.
• W1799665930 cites W2060476201 @default.
• W1799665930 cites W2065949088 @default.
• W1799665930 cites W2089100055 @default.
• W1799665930 cites W2090124061 @default.
• W1799665930 cites W2116190042 @default.
• W1799665930 cites W2119541227 @default.
• W1799665930 cites W2135330383 @default.
• W1799665930 cites W2148305346 @default.
• W1799665930 cites W2156182651 @default.
• W1799665930 cites W4229653650 @default.
• W1799665930 cites W4249117658 @default.
• W1799665930 cites W4296928399 @default.
• W1799665930 doi "https://doi.org/10.1111/j.1600-079x.2011.00863.x" @default.
• W1799665930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21392091" @default.
• W1799665930 hasPublicationYear "2011" @default.
• W1799665930 type Work @default.
• W1799665930 sameAs 1799665930 @default.
• W1799665930 citedByCount "37" @default.
• W1799665930 countsByYear W17996659302012 @default.
• W1799665930 countsByYear W17996659302013 @default.
• W1799665930 countsByYear W17996659302014 @default.
• W1799665930 countsByYear W17996659302015 @default.
• W1799665930 countsByYear W17996659302016 @default.
• W1799665930 countsByYear W17996659302017 @default.
• W1799665930 countsByYear W17996659302018 @default.
• W1799665930 countsByYear W17996659302019 @default.
• W1799665930 countsByYear W17996659302020 @default.
• W1799665930 countsByYear W17996659302021 @default.
• W1799665930 countsByYear W17996659302022 @default.
• W1799665930 countsByYear W17996659302023 @default.
• W1799665930 crossrefType "journal-article" @default.
• W1799665930 hasAuthorship W1799665930A5008231346 @default.
• W1799665930 hasAuthorship W1799665930A5024257143 @default.
• W1799665930 hasAuthorship W1799665930A5050487933 @default.
• W1799665930 hasAuthorship W1799665930A5051082508 @default.
• W1799665930 hasAuthorship W1799665930A5060165452 @default.
• W1799665930 hasAuthorship W1799665930A5072439406 @default.
• W1799665930 hasAuthorship W1799665930A5076408469 @default.
• W1799665930 hasAuthorship W1799665930A5083830540 @default.
• W1799665930 hasConcept C126322002 @default.
• W1799665930 hasConcept C134018914 @default.
• W1799665930 hasConcept C2776153327 @default.
• W1799665930 hasConcept C2777628635 @default.
• W1799665930 hasConcept C2778182776 @default.
• W1799665930 hasConcept C2778384902 @default.
• W1799665930 hasConcept C2779949491 @default.
• W1799665930 hasConcept C2780835948 @default.
• W1799665930 hasConcept C519581460 @default.
• W1799665930 hasConcept C71924100 @default.
• W1799665930 hasConceptScore W1799665930C126322002 @default.
• W1799665930 hasConceptScore W1799665930C134018914 @default.
• W1799665930 hasConceptScore W1799665930C2776153327 @default.
• W1799665930 hasConceptScore W1799665930C2777628635 @default.
• W1799665930 hasConceptScore W1799665930C2778182776 @default.
• W1799665930 hasConceptScore W1799665930C2778384902 @default.
• W1799665930 hasConceptScore W1799665930C2779949491 @default.
• W1799665930 hasConceptScore W1799665930C2780835948 @default.
• W1799665930 hasConceptScore W1799665930C519581460 @default.
• W1799665930 hasConceptScore W1799665930C71924100 @default.
• W1799665930 hasIssue "4" @default.
• W1799665930 hasLocation W17996659301 @default.
• W1799665930 hasLocation W17996659302 @default.
• W1799665930 hasOpenAccess W1799665930 @default.
• W1799665930 hasPrimaryLocation W17996659301 @default.
• W1799665930 hasRelatedWork W2030016272 @default.
• W1799665930 hasRelatedWork W2048527381 @default.
• W1799665930 hasRelatedWork W2051363066 @default.

• next