FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1801206013> ?p ?o ?g. }

• W1801206013 endingPage "5316" @default.
• W1801206013 startingPage "5307" @default.
• W1801206013 abstract "Prior experimental strategies to induce transplantation tolerance have focused largely on modifying adaptive immunity. However, less is known concerning the role of innate immune signaling in the induction of transplantation tolerance. Using a highly immunogenic murine skin transplant model that resists transplantation tolerance induction when innate immunity is preserved, we show that absence of MyD88, a key innate Toll like receptor signal adaptor, abrogates this resistance and facilitates inducible allograft acceptance. In our model, absence of MyD88 impairs inflammatory dendritic cell responses that reduce T cell activation. This effect increases T cell susceptibility to suppression mediated by CD4+ CD25+ regulatory T cells. Therefore, this study provides evidence that absence of MyD88 promotes inducible allograft acceptance and implies that inhibiting innate immunity may be a potential, clinically relevant strategy to facilitate transplantation tolerance." @default.
• W1801206013 created "2016-06-24" @default.
• W1801206013 creator A5005488593 @default.
• W1801206013 creator A5028923883 @default.
• W1801206013 creator A5043081740 @default.
• W1801206013 creator A5047578758 @default.
• W1801206013 creator A5072335233 @default.
• W1801206013 creator A5091687132 @default.
• W1801206013 date "2006-10-15" @default.
• W1801206013 modified "2023-10-03" @default.
• W1801206013 title "Absence of Innate MyD88 Signaling Promotes Inducible Allograft Acceptance" @default.
• W1801206013 cites W1525912444 @default.
• W1801206013 cites W1543352581 @default.
• W1801206013 cites W1574234266 @default.
• W1801206013 cites W1700278844 @default.
• W1801206013 cites W1723158139 @default.
• W1801206013 cites W1939193319 @default.
• W1801206013 cites W1979035865 @default.
• W1801206013 cites W1988461505 @default.
• W1801206013 cites W1996736315 @default.
• W1801206013 cites W2001740313 @default.
• W1801206013 cites W2002386322 @default.
• W1801206013 cites W2004465286 @default.
• W1801206013 cites W2004773897 @default.
• W1801206013 cites W2008390343 @default.
• W1801206013 cites W2021961375 @default.
• W1801206013 cites W2025412364 @default.
• W1801206013 cites W2046944378 @default.
• W1801206013 cites W2049053823 @default.
• W1801206013 cites W2060038284 @default.
• W1801206013 cites W2067773447 @default.
• W1801206013 cites W2070597700 @default.
• W1801206013 cites W2074592831 @default.
• W1801206013 cites W2083380291 @default.
• W1801206013 cites W2090640877 @default.
• W1801206013 cites W2110753254 @default.
• W1801206013 cites W2112473359 @default.
• W1801206013 cites W2118637098 @default.
• W1801206013 cites W2130322182 @default.
• W1801206013 cites W2131124022 @default.
• W1801206013 cites W2133523105 @default.
• W1801206013 cites W2135921495 @default.
• W1801206013 cites W2153410053 @default.
• W1801206013 cites W2155779547 @default.
• W1801206013 cites W2167258631 @default.
• W1801206013 cites W2169118161 @default.
• W1801206013 cites W4211218508 @default.
• W1801206013 cites W4242872472 @default.
• W1801206013 cites W4243801727 @default.
• W1801206013 cites W4244074296 @default.
• W1801206013 cites W4246291556 @default.
• W1801206013 cites W4313342469 @default.
• W1801206013 doi "https://doi.org/10.4049/jimmunol.177.8.5307" @default.
• W1801206013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17015716" @default.
• W1801206013 hasPublicationYear "2006" @default.
• W1801206013 type Work @default.
• W1801206013 sameAs 1801206013 @default.
• W1801206013 citedByCount "108" @default.
• W1801206013 countsByYear W18012060132012 @default.
• W1801206013 countsByYear W18012060132013 @default.
• W1801206013 countsByYear W18012060132014 @default.
• W1801206013 countsByYear W18012060132015 @default.
• W1801206013 countsByYear W18012060132016 @default.
• W1801206013 countsByYear W18012060132017 @default.
• W1801206013 countsByYear W18012060132018 @default.
• W1801206013 countsByYear W18012060132019 @default.
• W1801206013 countsByYear W18012060132020 @default.
• W1801206013 countsByYear W18012060132021 @default.
• W1801206013 countsByYear W18012060132022 @default.
• W1801206013 countsByYear W18012060132023 @default.
• W1801206013 crossrefType "journal-article" @default.
• W1801206013 hasAuthorship W1801206013A5005488593 @default.
• W1801206013 hasAuthorship W1801206013A5028923883 @default.
• W1801206013 hasAuthorship W1801206013A5043081740 @default.
• W1801206013 hasAuthorship W1801206013A5047578758 @default.
• W1801206013 hasAuthorship W1801206013A5072335233 @default.
• W1801206013 hasAuthorship W1801206013A5091687132 @default.
• W1801206013 hasBestOaLocation W18012060131 @default.
• W1801206013 hasConcept C126322002 @default.
• W1801206013 hasConcept C136449434 @default.
• W1801206013 hasConcept C193419808 @default.
• W1801206013 hasConcept C203014093 @default.
• W1801206013 hasConcept C2779341262 @default.
• W1801206013 hasConcept C2911091166 @default.
• W1801206013 hasConcept C62478195 @default.
• W1801206013 hasConcept C71924100 @default.
• W1801206013 hasConcept C86803240 @default.
• W1801206013 hasConcept C8891405 @default.
• W1801206013 hasConcept C95444343 @default.
• W1801206013 hasConceptScore W1801206013C126322002 @default.
• W1801206013 hasConceptScore W1801206013C136449434 @default.
• W1801206013 hasConceptScore W1801206013C193419808 @default.
• W1801206013 hasConceptScore W1801206013C203014093 @default.
• W1801206013 hasConceptScore W1801206013C2779341262 @default.
• W1801206013 hasConceptScore W1801206013C2911091166 @default.
• W1801206013 hasConceptScore W1801206013C62478195 @default.
• W1801206013 hasConceptScore W1801206013C71924100 @default.
• W1801206013 hasConceptScore W1801206013C86803240 @default.

• next