FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W180147998> ?p ?o ?g. }

• W180147998 endingPage "88" @default.
• W180147998 startingPage "179" @default.
• W180147998 abstract "Lymphocytes stimulated with concanavalin A (Con A) or antigen in the presence of bovine parainfluenza virus type 3 (PIV-3) infected bovine alveolar macrophages (BAM) or monocytes, had depressed [3H]thymidine incorporation. This failure of lymphocytes to incorporate radiolabel required live virus, was time dependent and was most pronounced when BAM were infected for 48 hr prior to the addition of lymphocytes. The rate of infection of alveolar macrophages and the release of infectious virus into culture supernatants paralleled suppression of lymphocyte mitogenesis by PIV-3. However, the peak titre of exogenous, live or inactivated virus was not suppressive when added to lymphocyte macrophage cultures just prior to Con A stimulation. Neither the loss of viable alveolar macrophages nor a shift in antigen or mitogen dose response in virally infected cultures could account for the deficit in [3H]thymidine incorporation by lymphocytes. Despite the presence of lymphocyte-associated virus antigen detected by direct immunofluorescence, no increase in PIV-3 titre above baseline was seen from infected lymphocytes, irrespective of mitogen stimulation. Likewise, lymphocytes did not contribute to the extracellular virus pool in lymphocyte-macrophage cultures as the increases in viral titre above basal levels in supernatants were equal to levels released by macrophages alone. The expression of viral antigen on lymphocytes stimulated in the presence of PIV-3-infected BAM suggests a non-productive or abortive infection of lymphocytes mediated through contact with infected macrophages." @default.
• W180147998 created "2016-06-24" @default.
• W180147998 creator A5025320941 @default.
• W180147998 creator A5033449288 @default.
• W180147998 creator A5051251351 @default.
• W180147998 creator A5063878607 @default.
• W180147998 creator A5071793980 @default.
• W180147998 creator A5074788853 @default.
• W180147998 date "1993-06-01" @default.
• W180147998 modified "2023-09-26" @default.
• W180147998 title "Suppression of lymphocyte proliferation by parainfluenza virus type 3-infected bovine alveolar macrophages." @default.
• W180147998 cites W1434937197 @default.
• W180147998 cites W1484285187 @default.
• W180147998 cites W1488936242 @default.
• W180147998 cites W1568919616 @default.
• W180147998 cites W1590413586 @default.
• W180147998 cites W1787921311 @default.
• W180147998 cites W1894302233 @default.
• W180147998 cites W1905668094 @default.
• W180147998 cites W1949707070 @default.
• W180147998 cites W1966842062 @default.
• W180147998 cites W1971342652 @default.
• W180147998 cites W1984907346 @default.
• W180147998 cites W1997004265 @default.
• W180147998 cites W2012762029 @default.
• W180147998 cites W2040606873 @default.
• W180147998 cites W2047613461 @default.
• W180147998 cites W2067304939 @default.
• W180147998 cites W2074685443 @default.
• W180147998 cites W2083017993 @default.
• W180147998 cites W2083549032 @default.
• W180147998 cites W2098413956 @default.
• W180147998 cites W2100452343 @default.
• W180147998 cites W2103152257 @default.
• W180147998 cites W2125884532 @default.
• W180147998 cites W2128891157 @default.
• W180147998 cites W2130656023 @default.
• W180147998 cites W2130946176 @default.
• W180147998 cites W2132046309 @default.
• W180147998 cites W2152169043 @default.
• W180147998 cites W2403146440 @default.
• W180147998 cites W2410309001 @default.
• W180147998 cites W2412043407 @default.
• W180147998 cites W2417866826 @default.
• W180147998 cites W2425907612 @default.
• W180147998 cites W1518816310 @default.
• W180147998 cites W2061579599 @default.
• W180147998 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1421871" @default.
• W180147998 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8393834" @default.
• W180147998 hasPublicationYear "1993" @default.
• W180147998 type Work @default.
• W180147998 sameAs 180147998 @default.
• W180147998 citedByCount "3" @default.
• W180147998 crossrefType "journal-article" @default.
• W180147998 hasAuthorship W180147998A5025320941 @default.
• W180147998 hasAuthorship W180147998A5033449288 @default.
• W180147998 hasAuthorship W180147998A5051251351 @default.
• W180147998 hasAuthorship W180147998A5063878607 @default.
• W180147998 hasAuthorship W180147998A5071793980 @default.
• W180147998 hasAuthorship W180147998A5074788853 @default.
• W180147998 hasConcept C134018914 @default.
• W180147998 hasConcept C147483822 @default.
• W180147998 hasConcept C159047783 @default.
• W180147998 hasConcept C159654299 @default.
• W180147998 hasConcept C19869320 @default.
• W180147998 hasConcept C202751555 @default.
• W180147998 hasConcept C203014093 @default.
• W180147998 hasConcept C24998067 @default.
• W180147998 hasConcept C2522874641 @default.
• W180147998 hasConcept C2777108182 @default.
• W180147998 hasConcept C2777761686 @default.
• W180147998 hasConcept C2778012055 @default.
• W180147998 hasConcept C2778236600 @default.
• W180147998 hasConcept C2778543330 @default.
• W180147998 hasConcept C2779244956 @default.
• W180147998 hasConcept C32611913 @default.
• W180147998 hasConcept C55493867 @default.
• W180147998 hasConcept C86803240 @default.
• W180147998 hasConcept C89423630 @default.
• W180147998 hasConceptScore W180147998C134018914 @default.
• W180147998 hasConceptScore W180147998C147483822 @default.
• W180147998 hasConceptScore W180147998C159047783 @default.
• W180147998 hasConceptScore W180147998C159654299 @default.
• W180147998 hasConceptScore W180147998C19869320 @default.
• W180147998 hasConceptScore W180147998C202751555 @default.
• W180147998 hasConceptScore W180147998C203014093 @default.
• W180147998 hasConceptScore W180147998C24998067 @default.
• W180147998 hasConceptScore W180147998C2522874641 @default.
• W180147998 hasConceptScore W180147998C2777108182 @default.
• W180147998 hasConceptScore W180147998C2777761686 @default.
• W180147998 hasConceptScore W180147998C2778012055 @default.
• W180147998 hasConceptScore W180147998C2778236600 @default.
• W180147998 hasConceptScore W180147998C2778543330 @default.
• W180147998 hasConceptScore W180147998C2779244956 @default.
• W180147998 hasConceptScore W180147998C32611913 @default.
• W180147998 hasConceptScore W180147998C55493867 @default.
• W180147998 hasConceptScore W180147998C86803240 @default.
• W180147998 hasConceptScore W180147998C89423630 @default.

• next