FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1801563508> ?p ?o ?g. }

• W1801563508 endingPage "2958" @default.
• W1801563508 startingPage "2951" @default.
• W1801563508 abstract "The transcription of the CYC7 gene of Saccharomyces cerevisiae, encoding the iso-2-cytochrome c protein, is controlled by two upstream regulatory elements, a positive element and a negative element. The nature of the DNA sequences in the negative element were investigated in a two-part approach. The first involved the construction of a CYC7-galK fusion gene which placed the coding sequence of the Escherichia coli galactokinase gene under the regulation of the CYC7 upstream sequences. This fusion allowed the quantitation by galactokinase enzyme assays of the effects on gene expression of a variety of previously isolated deletion mutations within the negative site. The results suggested that the negative site contained three related sequences. This hypothesis was tested in the second part of these studies, the selection of point mutations within the region of the negative site which led to increased CYC7 expression. Point mutations were introduced by a technique which induced mutations within a localized region at high efficiency. All but one of the mutations involved more than a single base-pair change. The mutations followed the pattern that multiple base-pair changes occurred in one repeat or single base-pair changes occurred in two repeats, with the exception of one mutant, which had a single base-pair change in one repeat. This pattern of mutations and the base pairs that were altered strongly supported the hypothesis that the repeats are integral elements of the negative site." @default.
• W1801563508 created "2016-06-24" @default.
• W1801563508 creator A5002386106 @default.
• W1801563508 creator A5005297303 @default.
• W1801563508 date "1985-11-01" @default.
• W1801563508 modified "2023-09-25" @default.
• W1801563508 title "Point mutations implicate repeated sequences as essential elements of the CYC7 negative upstream site in Saccharomyces cerevisiae." @default.
• W1801563508 cites W1491790057 @default.
• W1801563508 cites W1605707346 @default.
• W1801563508 cites W1781717284 @default.
• W1801563508 cites W1817433838 @default.
• W1801563508 cites W1953413771 @default.
• W1801563508 cites W1959595138 @default.
• W1801563508 cites W1971589776 @default.
• W1801563508 cites W1973782344 @default.
• W1801563508 cites W1974065319 @default.
• W1801563508 cites W1979301724 @default.
• W1801563508 cites W1986586522 @default.
• W1801563508 cites W1986949138 @default.
• W1801563508 cites W1987056309 @default.
• W1801563508 cites W2002369389 @default.
• W1801563508 cites W2003436052 @default.
• W1801563508 cites W2006836034 @default.
• W1801563508 cites W2009045393 @default.
• W1801563508 cites W2014422051 @default.
• W1801563508 cites W2023773243 @default.
• W1801563508 cites W2023893656 @default.
• W1801563508 cites W2026642300 @default.
• W1801563508 cites W2037320704 @default.
• W1801563508 cites W2038886368 @default.
• W1801563508 cites W2050499271 @default.
• W1801563508 cites W2052993533 @default.
• W1801563508 cites W2065723356 @default.
• W1801563508 cites W2076784340 @default.
• W1801563508 cites W2084742641 @default.
• W1801563508 cites W2092239792 @default.
• W1801563508 cites W2101278035 @default.
• W1801563508 cites W2132417094 @default.
• W1801563508 cites W2138270253 @default.
• W1801563508 cites W2154111763 @default.
• W1801563508 cites W2413731258 @default.
• W1801563508 cites W3135974194 @default.
• W1801563508 cites W2090920017 @default.
• W1801563508 doi "https://doi.org/10.1128/mcb.5.11.2951" @default.
• W1801563508 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/369106" @default.
• W1801563508 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3018489" @default.
• W1801563508 hasPublicationYear "1985" @default.
• W1801563508 type Work @default.
• W1801563508 sameAs 1801563508 @default.
• W1801563508 citedByCount "23" @default.
• W1801563508 crossrefType "journal-article" @default.
• W1801563508 hasAuthorship W1801563508A5002386106 @default.
• W1801563508 hasAuthorship W1801563508A5005297303 @default.
• W1801563508 hasBestOaLocation W18015635082 @default.
• W1801563508 hasConcept C104317684 @default.
• W1801563508 hasConcept C111829193 @default.
• W1801563508 hasConcept C143065580 @default.
• W1801563508 hasConcept C153911025 @default.
• W1801563508 hasConcept C167625842 @default.
• W1801563508 hasConcept C176944494 @default.
• W1801563508 hasConcept C185581394 @default.
• W1801563508 hasConcept C196493046 @default.
• W1801563508 hasConcept C2777576037 @default.
• W1801563508 hasConcept C54355233 @default.
• W1801563508 hasConcept C547475151 @default.
• W1801563508 hasConcept C54985914 @default.
• W1801563508 hasConcept C86803240 @default.
• W1801563508 hasConcept C91779695 @default.
• W1801563508 hasConceptScore W1801563508C104317684 @default.
• W1801563508 hasConceptScore W1801563508C111829193 @default.
• W1801563508 hasConceptScore W1801563508C143065580 @default.
• W1801563508 hasConceptScore W1801563508C153911025 @default.
• W1801563508 hasConceptScore W1801563508C167625842 @default.
• W1801563508 hasConceptScore W1801563508C176944494 @default.
• W1801563508 hasConceptScore W1801563508C185581394 @default.
• W1801563508 hasConceptScore W1801563508C196493046 @default.
• W1801563508 hasConceptScore W1801563508C2777576037 @default.
• W1801563508 hasConceptScore W1801563508C54355233 @default.
• W1801563508 hasConceptScore W1801563508C547475151 @default.
• W1801563508 hasConceptScore W1801563508C54985914 @default.
• W1801563508 hasConceptScore W1801563508C86803240 @default.
• W1801563508 hasConceptScore W1801563508C91779695 @default.
• W1801563508 hasIssue "11" @default.
• W1801563508 hasLocation W18015635081 @default.
• W1801563508 hasLocation W18015635082 @default.
• W1801563508 hasOpenAccess W1801563508 @default.
• W1801563508 hasPrimaryLocation W18015635081 @default.
• W1801563508 hasRelatedWork W17862870 @default.
• W1801563508 hasRelatedWork W1801563508 @default.
• W1801563508 hasRelatedWork W1865915409 @default.
• W1801563508 hasRelatedWork W1971610072 @default.
• W1801563508 hasRelatedWork W1972681927 @default.
• W1801563508 hasRelatedWork W1973423104 @default.
• W1801563508 hasRelatedWork W2002237446 @default.
• W1801563508 hasRelatedWork W2005527319 @default.
• W1801563508 hasRelatedWork W2337602892 @default.
• W1801563508 hasRelatedWork W4238829765 @default.
• W1801563508 hasVolume "5" @default.

• next