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- W1803293150 abstract "Introduction Most adult sleep laboratories do not measure carbon dioxide (CO 2 ) routinely during polygraphy (PG). In children, CO 2 measurements are “recommended” but few studies have analyzed systematic CO 2 monitoring during PG. Objectives The aim of the study was to assess the prevalence and predictors of nocturnal hypercapnia in children with sleep-disordered breathing (SDB). Methods Systematic transcutaneous CO 2 (PtcCO 2 ) monitoring was performed during overnight PG. Three definitions of nocturnal hypercapnia were used: a maximal PtcCO 2 >50 mmHg, percentage of sleep time with PtcCO 2 >50 mmHg >2%, and a PtcCO 2 >10 mmHg above waking baseline level. PtcCO 2 indices were correlated to the apnoea-hypopnoea index (AHI) and oxygenation indices (desaturation index, minimal SpO 2 and percentage of time with SpO 2 Results 221 PGs from patients with suspicion of obstructive sleep apnoea (72%), neuromuscular (21%) and lung diseases (7%) were analyzed. The percentage of hypercapnic patients ranged between 20 and 60%, and was not different between groups whatever the definition of hypercapnia. Significant but weak correlations were observed between hypercapnia according to the 3 definitions and the AHI (r=0.137, p=0.047 for maximal PtcCO 2 ) and oxygenation indices. The Receiver operating characteristic curves showed a poor sensitivity and specificity of the AHI and SpO 2 to predict nocturnal hypercapnia. Conclusion This study shows that 20 to 60% of children undergoing an overnight PG for SDB have nocturnal hypercapnia which is poorly correlated to the AHI and oxygenation indices. A systematic nocturnal CO 2 recording is useful in all children presenting with SDB, whatever the underlying disease." @default.
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- W1803293150 date "2013-09-01" @default.
- W1803293150 modified "2023-09-30" @default.
- W1803293150 title "Carbon dioxide monitoring during polygraphy in children with sleep-disordered breathing: Is it necessary?" @default.
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