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- W1803402068 abstract "We describe a 58-year-old man with tularemia and expanding gamma delta T cells in his peripheral blood lymphocytes (PBL) (32.7% of total PBL). In the present work, we analyzed the T-cell receptor V gamma/V delta repertoire of these cells by making use of the polymerase chain reaction and flow cytometry and found that they were mostly CD4- CD8- CD3+ V gamma 9/V delta 2+. The sequence analysis of 16 cDNA clones encoding the V gamma 9-J region revealed that the V gamma 9-Jp combination was strikingly overrepresented but that the junctional (N) region was heterogeneous. This suggested that the gamma delta T cells in PBL from a patient with tularemia were polyclonally expanded." @default.
- W1803402068 created "2016-06-24" @default.
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- W1803402068 date "1992-06-01" @default.
- W1803402068 modified "2023-10-16" @default.
- W1803402068 title "Predominant expansion of V gamma 9/V delta 2 T cells in a tularemia patient" @default.
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- W1803402068 doi "https://doi.org/10.1128/iai.60.6.2554-2558.1992" @default.
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