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- W180366481 abstract "Selenium is an essential trace element in human and animal nutrition and an integral component of antioxidative proteins. Organic selenium, a natural form of selenium, has more beneficial effects in maintaining antioxidative system than its inorganic form. The objective of this study was to examine the effect of organic selenium food supplements on the level of glutathione peroxidase (GSH-Px), glutathione (GSH) and lipid peroxides (TBARS) in chicken whole blood. Chickens were randomly allocated into two groups: standard diets (<0.15 ppm sodium selenite) fed control group (n = 40) and Se+ group (n = 40), fed the same diets supplemented with 0.3 ppm organic selenium. Ten randomly selected birds from each group at the age of two, four and six weeks and after 48-hours of food deprivation at the end of the fattening period, were subjected to blood withdrawal from jugular vein. The GSH-Px activity and concentrations of GSH and TBARS were analyzed by spectrophotometry. A trend was observed toward increasing GSH-Px in the blood of the control group from two to six weeks of age (P<0.001), whereas in the Se+ group the increase was obtained in the first four weeks (P<0.01). GSH-Px activity after fasting was lower only in the control chickens ( P<0.01). Organic selenium supplementation resulted in higher GSH-Px activity at two and four weeks of age (P<0.01), as well as after fasting (P<0.01). The GSH level in four week old Se+ chickens was lower than in two and six week old broilers ( P<0.01). At the same time, in the two week old control chickens higher values were recorded in comparison with older birds (P<0.05). After fasting, the GSH was lower in both groups of chickens compared to values given after the end of the fattening period (P<0.001). The TBARS decreased in concentration in both groups at six weeks of age compared to younger chickens (P<0.05). Dietary organic selenium supplementation manifested higher activity of GSH-Px during fattening and maintaining its activity in stress conditions provoked" @default.
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- W180366481 date "2008-01-01" @default.
- W180366481 modified "2023-09-22" @default.
- W180366481 title "Effect of organic selenium supplementation on antioxidative characteristics and lipid peroxidation of chicken blood during fattening and after fasting" @default.
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