Matches in SemOpenAlex for { <https://semopenalex.org/work/W1805452570> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1805452570 endingPage "12" @default.
- W1805452570 startingPage "2406" @default.
- W1805452570 abstract "Functional antimuscarinic receptor autoantibodies have recently been described in both primary and secondary Sjögren's syndrome (SS) in a mouse bladder contraction assay. Most patients with these antibodies complained of severe lower urinary tract disturbances, which are not a recognized feature of SS. We compared the severity of self-reported urological symptoms, daytime somnolence, and fatigue between a cohort of patients with primary SS and controls with osteoarthritis (OA).Female patients were recruited from rheumatology outpatient clinics at 2 hospitals. The American Urological Symptom Index (AUA-7), Epworth Sleepiness Scale, and FACIT-F fatigue self-administered instruments were employed. Results were obtained for 76 patients with primary SS and 43 controls (response rates 85% and 67%, respectively). The patient groups were matched for parity, hormone replacement and diuretic therapy, and number of bladder operations and urinary tract infections, although OA patients were slightly older.AUA-7 urological symptoms were more severe in patients with primary SS compared to OA controls (p = 0.039). Severe urological symptoms were reported by 61% of primary SS patients compared with 40% of OA controls. This difference was predominantly attributable to bladder irritability associated with urgency (p = 0.015) and not nocturia (p = 0.85). Epworth Sleepiness Scale scores were also more severe in primary SS patients compared to OA controls (p = 0.02), independent of nocturia. The FACIT-F fatigue severity scores were not significantly different between patient groups (p = 0.14).Urological symptoms and daytime somnolence may be previously unrecognized symptoms of primary SS. These symptoms are consistent with functional disturbances of muscarinic receptors, possibly mediated by muscarinic receptor autoantibodies." @default.
- W1805452570 created "2016-06-24" @default.
- W1805452570 creator A5003847558 @default.
- W1805452570 creator A5025007671 @default.
- W1805452570 creator A5045129087 @default.
- W1805452570 creator A5073888102 @default.
- W1805452570 creator A5074232296 @default.
- W1805452570 creator A5078271584 @default.
- W1805452570 creator A5079672756 @default.
- W1805452570 creator A5086044066 @default.
- W1805452570 date "2003-11-01" @default.
- W1805452570 modified "2023-09-27" @default.
- W1805452570 title "Increased severity of lower urinary tract symptoms and daytime somnolence in primary Sjögren's syndrome." @default.
- W1805452570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14677185" @default.
- W1805452570 hasPublicationYear "2003" @default.
- W1805452570 type Work @default.
- W1805452570 sameAs 1805452570 @default.
- W1805452570 citedByCount "17" @default.
- W1805452570 countsByYear W18054525702012 @default.
- W1805452570 countsByYear W18054525702013 @default.
- W1805452570 countsByYear W18054525702014 @default.
- W1805452570 countsByYear W18054525702016 @default.
- W1805452570 countsByYear W18054525702019 @default.
- W1805452570 countsByYear W18054525702020 @default.
- W1805452570 countsByYear W18054525702021 @default.
- W1805452570 countsByYear W18054525702022 @default.
- W1805452570 crossrefType "journal-article" @default.
- W1805452570 hasAuthorship W1805452570A5003847558 @default.
- W1805452570 hasAuthorship W1805452570A5025007671 @default.
- W1805452570 hasAuthorship W1805452570A5045129087 @default.
- W1805452570 hasAuthorship W1805452570A5073888102 @default.
- W1805452570 hasAuthorship W1805452570A5074232296 @default.
- W1805452570 hasAuthorship W1805452570A5078271584 @default.
- W1805452570 hasAuthorship W1805452570A5079672756 @default.
- W1805452570 hasAuthorship W1805452570A5086044066 @default.
- W1805452570 hasConcept C121608353 @default.
- W1805452570 hasConcept C126322002 @default.
- W1805452570 hasConcept C142724271 @default.
- W1805452570 hasConcept C197934379 @default.
- W1805452570 hasConcept C198451711 @default.
- W1805452570 hasConcept C204787440 @default.
- W1805452570 hasConcept C2776235491 @default.
- W1805452570 hasConcept C2777333188 @default.
- W1805452570 hasConcept C2778205975 @default.
- W1805452570 hasConcept C2778562196 @default.
- W1805452570 hasConcept C2778664715 @default.
- W1805452570 hasConcept C2778941218 @default.
- W1805452570 hasConcept C2779034229 @default.
- W1805452570 hasConcept C2779478474 @default.
- W1805452570 hasConcept C2780820931 @default.
- W1805452570 hasConcept C2781326671 @default.
- W1805452570 hasConcept C3020110884 @default.
- W1805452570 hasConcept C71924100 @default.
- W1805452570 hasConcept C72563966 @default.
- W1805452570 hasConcept C77411442 @default.
- W1805452570 hasConcept C90924648 @default.
- W1805452570 hasConceptScore W1805452570C121608353 @default.
- W1805452570 hasConceptScore W1805452570C126322002 @default.
- W1805452570 hasConceptScore W1805452570C142724271 @default.
- W1805452570 hasConceptScore W1805452570C197934379 @default.
- W1805452570 hasConceptScore W1805452570C198451711 @default.
- W1805452570 hasConceptScore W1805452570C204787440 @default.
- W1805452570 hasConceptScore W1805452570C2776235491 @default.
- W1805452570 hasConceptScore W1805452570C2777333188 @default.
- W1805452570 hasConceptScore W1805452570C2778205975 @default.
- W1805452570 hasConceptScore W1805452570C2778562196 @default.
- W1805452570 hasConceptScore W1805452570C2778664715 @default.
- W1805452570 hasConceptScore W1805452570C2778941218 @default.
- W1805452570 hasConceptScore W1805452570C2779034229 @default.
- W1805452570 hasConceptScore W1805452570C2779478474 @default.
- W1805452570 hasConceptScore W1805452570C2780820931 @default.
- W1805452570 hasConceptScore W1805452570C2781326671 @default.
- W1805452570 hasConceptScore W1805452570C3020110884 @default.
- W1805452570 hasConceptScore W1805452570C71924100 @default.
- W1805452570 hasConceptScore W1805452570C72563966 @default.
- W1805452570 hasConceptScore W1805452570C77411442 @default.
- W1805452570 hasConceptScore W1805452570C90924648 @default.
- W1805452570 hasIssue "11" @default.
- W1805452570 hasLocation W18054525701 @default.
- W1805452570 hasOpenAccess W1805452570 @default.
- W1805452570 hasPrimaryLocation W18054525701 @default.
- W1805452570 hasRelatedWork W1805452570 @default.
- W1805452570 hasRelatedWork W1969228341 @default.
- W1805452570 hasRelatedWork W2017579314 @default.
- W1805452570 hasRelatedWork W2103771549 @default.
- W1805452570 hasRelatedWork W2108791951 @default.
- W1805452570 hasRelatedWork W2407249667 @default.
- W1805452570 hasRelatedWork W2756827299 @default.
- W1805452570 hasRelatedWork W2801518624 @default.
- W1805452570 hasRelatedWork W3029258591 @default.
- W1805452570 hasRelatedWork W4283789223 @default.
- W1805452570 hasVolume "30" @default.
- W1805452570 isParatext "false" @default.
- W1805452570 isRetracted "false" @default.
- W1805452570 magId "1805452570" @default.
- W1805452570 workType "article" @default.