Matches in SemOpenAlex for { <https://semopenalex.org/work/W180597712> ?p ?o ?g. }
- W180597712 abstract "Abstract : Circadian rhythms are endogenous rhythms in physiology or behavior with a cycle length near 24 hours. Circadian rhythms are relevant to military activities because the ability of military personnel to maintain high level of cognitive performance and vigilance for long intervals is degraded by human factors, including fatigue, sleep loss and other circadian factors. Underlying circadian rhythmicity is a molecular feedback loop. This project developed mathematical models of the mammalian circadian oscillator. Our approach was to gather information on parameters needed for model development through biochemical experiments, develop mathematical models of the mammalian circadian oscillator, and experimentally test predictions from these models. We created a reduced molecular model, with the long-term objective of incorporating a molecular model into an existing model of the influence of light and rhythmicity on human performance. Our experimental and modeling efforts led to several publications and the contribution of software for numerous circadian models to BioSpice. Understanding of the circadian oscillatory mechanism has the potential for new strategies in resetting the circadian clock to promote alertness and to enhance physiological synchronization to new environments after transmeridian travel. Our development of detailed molecular models of the mammalian clock provides an important first step towards these objectives." @default.
- W180597712 created "2016-06-24" @default.
- W180597712 creator A5070571965 @default.
- W180597712 date "2005-05-01" @default.
- W180597712 modified "2023-09-24" @default.
- W180597712 title "Development and Validation of a Computational Model for Intra-Cellular Circadian Oscillators" @default.
- W180597712 cites W1575619134 @default.
- W180597712 cites W1629086938 @default.
- W180597712 cites W1744822607 @default.
- W180597712 cites W1890508363 @default.
- W180597712 cites W1970130379 @default.
- W180597712 cites W1973788573 @default.
- W180597712 cites W1978248876 @default.
- W180597712 cites W1979383466 @default.
- W180597712 cites W1989011389 @default.
- W180597712 cites W1993885023 @default.
- W180597712 cites W2003302378 @default.
- W180597712 cites W2007334358 @default.
- W180597712 cites W2009132775 @default.
- W180597712 cites W2013855904 @default.
- W180597712 cites W2017211549 @default.
- W180597712 cites W2017428033 @default.
- W180597712 cites W2021229976 @default.
- W180597712 cites W2021654192 @default.
- W180597712 cites W2026162041 @default.
- W180597712 cites W2029599163 @default.
- W180597712 cites W2035809873 @default.
- W180597712 cites W2040650438 @default.
- W180597712 cites W2041136510 @default.
- W180597712 cites W2047279254 @default.
- W180597712 cites W2054513544 @default.
- W180597712 cites W2066440682 @default.
- W180597712 cites W2074539768 @default.
- W180597712 cites W2083117595 @default.
- W180597712 cites W2083647315 @default.
- W180597712 cites W2084772782 @default.
- W180597712 cites W2086349492 @default.
- W180597712 cites W2086473844 @default.
- W180597712 cites W2088907143 @default.
- W180597712 cites W2090816060 @default.
- W180597712 cites W2101546531 @default.
- W180597712 cites W2104290916 @default.
- W180597712 cites W2104725749 @default.
- W180597712 cites W2105640293 @default.
- W180597712 cites W2112215450 @default.
- W180597712 cites W2113297137 @default.
- W180597712 cites W2118646967 @default.
- W180597712 cites W2121847288 @default.
- W180597712 cites W2123160338 @default.
- W180597712 cites W2128500966 @default.
- W180597712 cites W2131647372 @default.
- W180597712 cites W2135694744 @default.
- W180597712 cites W2137252071 @default.
- W180597712 cites W2139766030 @default.
- W180597712 cites W2143506081 @default.
- W180597712 cites W2145348595 @default.
- W180597712 cites W2152043154 @default.
- W180597712 cites W2159280477 @default.
- W180597712 cites W2159545621 @default.
- W180597712 cites W2167008303 @default.
- W180597712 doi "https://doi.org/10.21236/ada435444" @default.
- W180597712 hasPublicationYear "2005" @default.
- W180597712 type Work @default.
- W180597712 sameAs 180597712 @default.
- W180597712 citedByCount "0" @default.
- W180597712 crossrefType "report" @default.
- W180597712 hasAuthorship W180597712A5070571965 @default.
- W180597712 hasConcept C121446783 @default.
- W180597712 hasConcept C130679736 @default.
- W180597712 hasConcept C169760540 @default.
- W180597712 hasConcept C200678441 @default.
- W180597712 hasConcept C38606739 @default.
- W180597712 hasConcept C41008148 @default.
- W180597712 hasConcept C63531555 @default.
- W180597712 hasConcept C86803240 @default.
- W180597712 hasConcept C98274493 @default.
- W180597712 hasConceptScore W180597712C121446783 @default.
- W180597712 hasConceptScore W180597712C130679736 @default.
- W180597712 hasConceptScore W180597712C169760540 @default.
- W180597712 hasConceptScore W180597712C200678441 @default.
- W180597712 hasConceptScore W180597712C38606739 @default.
- W180597712 hasConceptScore W180597712C41008148 @default.
- W180597712 hasConceptScore W180597712C63531555 @default.
- W180597712 hasConceptScore W180597712C86803240 @default.
- W180597712 hasConceptScore W180597712C98274493 @default.
- W180597712 hasLocation W1805977121 @default.
- W180597712 hasOpenAccess W180597712 @default.
- W180597712 hasPrimaryLocation W1805977121 @default.
- W180597712 hasRelatedWork W1964047636 @default.
- W180597712 hasRelatedWork W1979662292 @default.
- W180597712 hasRelatedWork W2007884363 @default.
- W180597712 hasRelatedWork W2035352715 @default.
- W180597712 hasRelatedWork W2124737554 @default.
- W180597712 hasRelatedWork W2398912119 @default.
- W180597712 hasRelatedWork W2589251569 @default.
- W180597712 hasRelatedWork W3021453809 @default.
- W180597712 hasRelatedWork W3043859478 @default.
- W180597712 hasRelatedWork W4234625062 @default.
- W180597712 isParatext "false" @default.
- W180597712 isRetracted "false" @default.