Matches in SemOpenAlex for { <https://semopenalex.org/work/W1806200417> ?p ?o ?g. }
- W1806200417 endingPage "17" @default.
- W1806200417 startingPage "9" @default.
- W1806200417 abstract "Most acinar cells and some duct cells undergo apoptosis during atrophy of the submandibular gland. The present study was designed to elucidate whether Fas and its receptor ligand (FasL) are involved during apoptotic atrophy of the gland. The excretory duct of the right submandibular gland of rats was doubly ligated with metal clips from 1 to 14 days for induction of gland atrophy. Control rats were untreated. Fas and FasL expression in the atrophied submandibular gland was detected using immunohistochemistry (IHC) and Western immunoblot. Expression of activated caspase 8 and activated caspase 3 was also detected with IHC. Fas-positive acinar and duct cells and FasL-positive duct cells increased in the atrophic glands at 3 and 5 days after duct ligation when apoptotic cells were commonly observed. Thereafter, Fas- and FasL-positive cells declined in number. Patterns of expression of Fas and FasL using Western immunoblots concurred with the IHC results. Activated caspase 8-positive cells were present at every time interval but peaked at 3 and 5 days following duct ligation. The cells showing immunoreaction for activated caspase 3 first appeared on day 3, with the peak in apoptosis, after which they decreased. The results indicate that the Fas/FasL systems likely play an important role in apoptotic pathways during atrophy of the submandibular gland." @default.
- W1806200417 created "2016-06-24" @default.
- W1806200417 creator A5001910883 @default.
- W1806200417 creator A5002044987 @default.
- W1806200417 creator A5060396947 @default.
- W1806200417 creator A5079170092 @default.
- W1806200417 creator A5087843682 @default.
- W1806200417 creator A5091773258 @default.
- W1806200417 date "2006-12-20" @default.
- W1806200417 modified "2023-10-18" @default.
- W1806200417 title "Participation of the Fas and Fas ligand systems in apoptosis during atrophy of the rat submandibular glands" @default.
- W1806200417 cites W102370904 @default.
- W1806200417 cites W1492302205 @default.
- W1806200417 cites W1517945724 @default.
- W1806200417 cites W1562354537 @default.
- W1806200417 cites W1671694443 @default.
- W1806200417 cites W1963688949 @default.
- W1806200417 cites W1966954962 @default.
- W1806200417 cites W1973109581 @default.
- W1806200417 cites W1978018492 @default.
- W1806200417 cites W1978471109 @default.
- W1806200417 cites W1980542725 @default.
- W1806200417 cites W1984573632 @default.
- W1806200417 cites W1988043250 @default.
- W1806200417 cites W1988757689 @default.
- W1806200417 cites W1991865867 @default.
- W1806200417 cites W1994680656 @default.
- W1806200417 cites W1995525938 @default.
- W1806200417 cites W2039986138 @default.
- W1806200417 cites W2049026112 @default.
- W1806200417 cites W2053224278 @default.
- W1806200417 cites W2054285048 @default.
- W1806200417 cites W2062008354 @default.
- W1806200417 cites W2075809552 @default.
- W1806200417 cites W2076229621 @default.
- W1806200417 cites W2098641105 @default.
- W1806200417 cites W2112460302 @default.
- W1806200417 cites W2113039096 @default.
- W1806200417 cites W2116875795 @default.
- W1806200417 cites W2140313671 @default.
- W1806200417 cites W2141566030 @default.
- W1806200417 cites W2145626047 @default.
- W1806200417 cites W2161261662 @default.
- W1806200417 cites W2164802863 @default.
- W1806200417 cites W2325028151 @default.
- W1806200417 cites W2326345088 @default.
- W1806200417 cites W2402060186 @default.
- W1806200417 cites W2409539114 @default.
- W1806200417 cites W2472731714 @default.
- W1806200417 doi "https://doi.org/10.1111/j.1365-2613.2006.00511.x" @default.
- W1806200417 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2517292" @default.
- W1806200417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17244334" @default.
- W1806200417 hasPublicationYear "2006" @default.
- W1806200417 type Work @default.
- W1806200417 sameAs 1806200417 @default.
- W1806200417 citedByCount "10" @default.
- W1806200417 countsByYear W18062004172015 @default.
- W1806200417 countsByYear W18062004172020 @default.
- W1806200417 countsByYear W18062004172021 @default.
- W1806200417 crossrefType "journal-article" @default.
- W1806200417 hasAuthorship W1806200417A5001910883 @default.
- W1806200417 hasAuthorship W1806200417A5002044987 @default.
- W1806200417 hasAuthorship W1806200417A5060396947 @default.
- W1806200417 hasAuthorship W1806200417A5079170092 @default.
- W1806200417 hasAuthorship W1806200417A5087843682 @default.
- W1806200417 hasAuthorship W1806200417A5091773258 @default.
- W1806200417 hasBestOaLocation W18062004172 @default.
- W1806200417 hasConcept C126322002 @default.
- W1806200417 hasConcept C134018914 @default.
- W1806200417 hasConcept C142724271 @default.
- W1806200417 hasConcept C190283241 @default.
- W1806200417 hasConcept C204232928 @default.
- W1806200417 hasConcept C2778937882 @default.
- W1806200417 hasConcept C2780266248 @default.
- W1806200417 hasConcept C2781172350 @default.
- W1806200417 hasConcept C2781212128 @default.
- W1806200417 hasConcept C31573885 @default.
- W1806200417 hasConcept C55493867 @default.
- W1806200417 hasConcept C66008609 @default.
- W1806200417 hasConcept C71924100 @default.
- W1806200417 hasConcept C86803240 @default.
- W1806200417 hasConceptScore W1806200417C126322002 @default.
- W1806200417 hasConceptScore W1806200417C134018914 @default.
- W1806200417 hasConceptScore W1806200417C142724271 @default.
- W1806200417 hasConceptScore W1806200417C190283241 @default.
- W1806200417 hasConceptScore W1806200417C204232928 @default.
- W1806200417 hasConceptScore W1806200417C2778937882 @default.
- W1806200417 hasConceptScore W1806200417C2780266248 @default.
- W1806200417 hasConceptScore W1806200417C2781172350 @default.
- W1806200417 hasConceptScore W1806200417C2781212128 @default.
- W1806200417 hasConceptScore W1806200417C31573885 @default.
- W1806200417 hasConceptScore W1806200417C55493867 @default.
- W1806200417 hasConceptScore W1806200417C66008609 @default.
- W1806200417 hasConceptScore W1806200417C71924100 @default.
- W1806200417 hasConceptScore W1806200417C86803240 @default.
- W1806200417 hasIssue "1" @default.
- W1806200417 hasLocation W18062004171 @default.
- W1806200417 hasLocation W18062004172 @default.