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- W1806992775 abstract "There is strong evidence that multistep tumorigenesis begins with the acquisition of somatic mutations which promote genomic instability. Genomic instability is an important malignant trait because genomic instability can generate the genetic diversity that is necessary for the transforming cell to acquire increasingly variable and aggressive tumor phenotypes. Genomic instability often manifests in the form of chromosomal instability (CIN) leading to the induction of aneuploidy, a phenomenon identified by high resolution molecular cytogenetic techniques. Fluorescent in situ hybridization (FISH) and Array Comparative Genomic Hybridization (aCGH) are two high resolution molecular cytogenetic techniques that allow detection of chromosomal aneuploidy and structural rearrangements occurring in pre-malignant and malignant lesions during tumor progression and invasion. These high resolution molecular cytogenetic techniques are used for genetic screening of single cells in pre-malignant and precursor malignant lesions as well as in exfoliated cells from body fluids and excreta. Consequently, molecular cytogenetic testing offers the promise of an extremely powerful method of risk assessment and early detection of cancer." @default.
- W1806992775 created "2016-06-24" @default.
- W1806992775 creator A5000815021 @default.
- W1806992775 creator A5039200530 @default.
- W1806992775 date "2011-10-26" @default.
- W1806992775 modified "2023-10-03" @default.
- W1806992775 title "Molecular cytogenetic evidence for multistep tumorigenesis: Implications for risk assessment and early detection" @default.
- W1806992775 cites W114795016 @default.
- W1806992775 cites W147310725 @default.
- W1806992775 cites W1484187172 @default.
- W1806992775 cites W1505392399 @default.
- W1806992775 cites W1510546584 @default.
- W1806992775 cites W1536563709 @default.
- W1806992775 cites W1542112366 @default.
- W1806992775 cites W1545398558 @default.
- W1806992775 cites W1551547047 @default.
- W1806992775 cites W1553178519 @default.
- W1806992775 cites W1556655356 @default.
- W1806992775 cites W1591150601 @default.
- W1806992775 cites W1837870834 @default.
- W1806992775 cites W1876434939 @default.
- W1806992775 cites W1959606306 @default.
- W1806992775 cites W1963941229 @default.
- W1806992775 cites W1966548019 @default.
- W1806992775 cites W1967304777 @default.
- W1806992775 cites W1970031355 @default.
- W1806992775 cites W1970564013 @default.
- W1806992775 cites W1970962471 @default.
- W1806992775 cites W1971474320 @default.
- W1806992775 cites W1975407466 @default.
- W1806992775 cites W1980447806 @default.
- W1806992775 cites W1983319967 @default.
- W1806992775 cites W1984328656 @default.
- W1806992775 cites W1984542357 @default.
- W1806992775 cites W1987369248 @default.
- W1806992775 cites W1990094886 @default.
- W1806992775 cites W1991069555 @default.
- W1806992775 cites W1991748238 @default.
- W1806992775 cites W1994365672 @default.
- W1806992775 cites W1995215272 @default.
- W1806992775 cites W1997813173 @default.
- W1806992775 cites W1998384280 @default.
- W1806992775 cites W1998593414 @default.
- W1806992775 cites W2003252913 @default.
- W1806992775 cites W2005413198 @default.
- W1806992775 cites W2006131916 @default.
- W1806992775 cites W2008297072 @default.
- W1806992775 cites W2014606320 @default.
- W1806992775 cites W2014968978 @default.
- W1806992775 cites W2015742586 @default.
- W1806992775 cites W2018514034 @default.
- W1806992775 cites W2018825948 @default.
- W1806992775 cites W2020092689 @default.
- W1806992775 cites W2021920872 @default.
- W1806992775 cites W2022527641 @default.
- W1806992775 cites W2023780438 @default.
- W1806992775 cites W2027803083 @default.
- W1806992775 cites W2028268632 @default.
- W1806992775 cites W2030202463 @default.
- W1806992775 cites W2030958510 @default.
- W1806992775 cites W2033860372 @default.
- W1806992775 cites W2034269086 @default.
- W1806992775 cites W2034696039 @default.
- W1806992775 cites W2035569367 @default.
- W1806992775 cites W2037479635 @default.
- W1806992775 cites W2041639227 @default.
- W1806992775 cites W2044368607 @default.
- W1806992775 cites W2046003313 @default.
- W1806992775 cites W2047928920 @default.
- W1806992775 cites W2049391622 @default.
- W1806992775 cites W2049820772 @default.
- W1806992775 cites W2050105240 @default.
- W1806992775 cites W2051296872 @default.
- W1806992775 cites W2055402151 @default.
- W1806992775 cites W2057782315 @default.
- W1806992775 cites W2058131725 @default.
- W1806992775 cites W2068727734 @default.
- W1806992775 cites W2069941672 @default.
- W1806992775 cites W2072363520 @default.
- W1806992775 cites W2075206831 @default.
- W1806992775 cites W2076372887 @default.
- W1806992775 cites W2077843410 @default.
- W1806992775 cites W2078615559 @default.
- W1806992775 cites W2079680569 @default.
- W1806992775 cites W2082534286 @default.
- W1806992775 cites W2084049578 @default.
- W1806992775 cites W2085515040 @default.
- W1806992775 cites W2089422349 @default.
- W1806992775 cites W2092158132 @default.
- W1806992775 cites W2099000927 @default.
- W1806992775 cites W2099380770 @default.
- W1806992775 cites W2099517538 @default.
- W1806992775 cites W2100849259 @default.
- W1806992775 cites W2101037339 @default.
- W1806992775 cites W2101131485 @default.
- W1806992775 cites W2102922697 @default.
- W1806992775 cites W2104853034 @default.
- W1806992775 cites W2107846106 @default.