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• W1807178664 abstract "Significance Drought is a major cause of lost agricultural productivity. Even moderate water limitation can lead to down-regulation of plant growth; however, the underlying mechanisms of stress sensing and growth regulation are little understood. We identified At14a-Like1 (AFL1) and its interacting proteins protein disulfide isomerase 5 (PDI5) and NAI2 as positive and negative regulators, respectively, of growth and proline accumulation. Despite numerous ideas that membrane-based mechanisms are important for drought sensing and initial signaling, AFL1 is one of only a few membrane proteins with a demonstrated effect on drought resistance. AFL1 structure, localization, and interaction with endomembrane proteins indicate novel functions in drought signaling. Increased growth of AFL1 overexpression in plants under stress without negative effects on unstressed plants make AFL1 an attractive target for biotechnology." @default.
• W1807178664 created "2016-06-24" @default.
• W1807178664 creator A5006579829 @default.
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• W1807178664 date "2015-08-03" @default.
• W1807178664 modified "2023-10-12" @default.
• W1807178664 title "At14a-Like1 participates in membrane-associated mechanisms promoting growth during drought in <i>Arabidopsis thaliana</i>" @default.
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• W1807178664 doi "https://doi.org/10.1073/pnas.1510140112" @default.
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