FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W180726677> ?p ?o ?g. }

• W180726677 endingPage "1350" @default.
• W180726677 startingPage "1345" @default.
• W180726677 abstract "Transanal excision of rectal villous adenomas is a widely used surgical technique, because it is a one-step procedure, requiring no sophisticated instrumentation, and allowing complete histologic analysis of the excised tumor. Therefore, it ranks alongside radical surgery and palliative destructive procedures, but its results are highly variable in the published series. This discrepancy may be explained by the variable completeness of tumor excision because of potential dissection difficulties. Because intraoperative exposure may be a major limiting factor, one of us (JF) has developed a tractable cutaneomucous flap procedure to lower the rectal tumor to the anal verge, where control of the dissection line is easier. This retrospective review of consecutive patients operated on during ten-year period reports long-term results after transanal excision for large rectal villous adenomas with the tractable flap technique.From 1978 to 1988, 207 consecutive patients (100 males), mean age 68 (range, 24-90) years, were operated on for an apparently benign villous rectal adenoma. Twenty-one patients (10 percent) were referred after failure of previous treatments: 11 endoscopic, 8 surgical, 1 laser, 1 radiotherapy. Mean distance of lower tumor edge from anal margin was 5.6 (range, 0-13) cm and was <10 cm in 82 percent.Three patients (1.5 percent), including one with a Tis carcinoma, underwent a secondary treatment for immediate gross failure of resection: one further local excision and two palliative laser destructions. Immediate postoperative course was uneventful for 96 percent; there was one death from perineal gangrenous infection, four cases of hemorrhage, and three urinary retentions. Subsequently one case of transient fecal incontinence and 11 medically managed stenoses were noted. Mean size of resected tumor was 5.4 (range, 1-17) cm. Deep excision margins concerned the rectal muscular layers in 199 patients (96 percent) and perirectal fat in 8 (4 percent). Specimen margins were negative for cancer in 175 (85 percent) and positive or unknown in 32 cases. Histologic evaluation demonstrated in situ cancer in 28 (14 percent) and invasive carcinoma in 9 (4 percent). In three patients (1 percent), two abdominoperineal resections were immediately performed (one T2 with a mucinous contingent, one T3) and one adjuvant radiotherapy (one undifferentiated T2). Four patients (2 percent) did not return for postoperative evaluation. For the remaining 198 patients, mean follow-up was 74 +/- 34 (median, 75; range, 1-168) months. Forty-four died from unrelated causes. Recurrence occurred in seven (3.6 percent) and was malignant in two, who subsequently died. Specific recurrence-free probability was 99.5 percent at one year, 96 percent at five years, and 95 percent at ten years. A lesion size >6 cm (10 vs. 1 percent for smaller tumors) and the presence of an invasive carcinoma (20 vs. 3 percent without invasive carcinoma) were significantly associated with an increased probability of recurrence at five years.Providing that adequate intraoperative exposure is obtained and advanced malignant tumors receive immediate secondary treatment, transanal resection of clinically benign, large rectal villous adenomas is safe and effective. It is an alternative to rectal resection, which exposes the patient to potentially adverse effects, and also to destructive procedures, which preclude any histologic evaluation of the tumor." @default.
• W180726677 created "2016-06-24" @default.
• W180726677 creator A5010885536 @default.
• W180726677 creator A5016505316 @default.
• W180726677 creator A5017654370 @default.
• W180726677 creator A5085239202 @default.
• W180726677 creator A5086596220 @default.
• W180726677 creator A5089459793 @default.
• W180726677 creator A5090274545 @default.
• W180726677 date "2003-10-01" @default.
• W180726677 modified "2023-10-10" @default.
• W180726677 title "Local Excision of Large Rectal Villous Adenomas" @default.
• W180726677 cites W1585448716 @default.
• W180726677 cites W180971096 @default.
• W180726677 cites W1967022481 @default.
• W180726677 cites W1970556192 @default.
• W180726677 cites W1976945635 @default.
• W180726677 cites W2009912942 @default.
• W180726677 cites W2012164445 @default.
• W180726677 cites W2023617551 @default.
• W180726677 cites W2027779774 @default.
• W180726677 cites W2053609422 @default.
• W180726677 cites W2069419100 @default.
• W180726677 cites W2073686619 @default.
• W180726677 cites W2078709097 @default.
• W180726677 cites W2081941304 @default.
• W180726677 cites W2086092215 @default.
• W180726677 cites W2315471885 @default.
• W180726677 cites W2398879619 @default.
• W180726677 cites W2413252416 @default.
• W180726677 cites W2417093902 @default.
• W180726677 cites W2741138670 @default.
• W180726677 cites W2883382584 @default.
• W180726677 cites W2912325655 @default.
• W180726677 doi "https://doi.org/10.1007/s10350-004-6748-1" @default.
• W180726677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14530673" @default.
• W180726677 hasPublicationYear "2003" @default.
• W180726677 type Work @default.
• W180726677 sameAs 180726677 @default.
• W180726677 citedByCount "48" @default.
• W180726677 countsByYear W1807266772013 @default.
• W180726677 countsByYear W1807266772015 @default.
• W180726677 countsByYear W1807266772016 @default.
• W180726677 countsByYear W1807266772017 @default.
• W180726677 countsByYear W1807266772018 @default.
• W180726677 countsByYear W1807266772019 @default.
• W180726677 countsByYear W1807266772021 @default.
• W180726677 countsByYear W1807266772022 @default.
• W180726677 crossrefType "journal-article" @default.
• W180726677 hasAuthorship W180726677A5010885536 @default.
• W180726677 hasAuthorship W180726677A5016505316 @default.
• W180726677 hasAuthorship W180726677A5017654370 @default.
• W180726677 hasAuthorship W180726677A5085239202 @default.
• W180726677 hasAuthorship W180726677A5086596220 @default.
• W180726677 hasAuthorship W180726677A5089459793 @default.
• W180726677 hasAuthorship W180726677A5090274545 @default.
• W180726677 hasConcept C121608353 @default.
• W180726677 hasConcept C126322002 @default.
• W180726677 hasConcept C141071460 @default.
• W180726677 hasConcept C159110652 @default.
• W180726677 hasConcept C2775862295 @default.
• W180726677 hasConcept C2777428134 @default.
• W180726677 hasConcept C2778132481 @default.
• W180726677 hasConcept C2780120127 @default.
• W180726677 hasConcept C2780914348 @default.
• W180726677 hasConcept C2781074409 @default.
• W180726677 hasConcept C2908689634 @default.
• W180726677 hasConcept C523026621 @default.
• W180726677 hasConcept C526805850 @default.
• W180726677 hasConcept C71924100 @default.
• W180726677 hasConceptScore W180726677C121608353 @default.
• W180726677 hasConceptScore W180726677C126322002 @default.
• W180726677 hasConceptScore W180726677C141071460 @default.
• W180726677 hasConceptScore W180726677C159110652 @default.
• W180726677 hasConceptScore W180726677C2775862295 @default.
• W180726677 hasConceptScore W180726677C2777428134 @default.
• W180726677 hasConceptScore W180726677C2778132481 @default.
• W180726677 hasConceptScore W180726677C2780120127 @default.
• W180726677 hasConceptScore W180726677C2780914348 @default.
• W180726677 hasConceptScore W180726677C2781074409 @default.
• W180726677 hasConceptScore W180726677C2908689634 @default.
• W180726677 hasConceptScore W180726677C523026621 @default.
• W180726677 hasConceptScore W180726677C526805850 @default.
• W180726677 hasConceptScore W180726677C71924100 @default.
• W180726677 hasIssue "10" @default.
• W180726677 hasLocation W1807266771 @default.
• W180726677 hasLocation W1807266772 @default.
• W180726677 hasOpenAccess W180726677 @default.
• W180726677 hasPrimaryLocation W1807266771 @default.
• W180726677 hasRelatedWork W1929238403 @default.
• W180726677 hasRelatedWork W2059356792 @default.
• W180726677 hasRelatedWork W2078709097 @default.
• W180726677 hasRelatedWork W2285494716 @default.
• W180726677 hasRelatedWork W2348027714 @default.
• W180726677 hasRelatedWork W2361600441 @default.
• W180726677 hasRelatedWork W2401273303 @default.
• W180726677 hasRelatedWork W2401376145 @default.
• W180726677 hasRelatedWork W2411069471 @default.

• next