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- W18085000 abstract "The inference of regulatory networks from microarray data relies on expression measures to identify gene activity patterns. However, currently existing xpression measures are not the direct measurements of mRNA concentration one would ideally need for an accurate determination of gene regulation. If the development of expression measures is to advance to the point where absolute target concentrations can be estimated, it is essential to have an understanding of physical processes leading to observed microarray data. We survey here the performance of existing expression measures for oligonucleotide microarrays and describe recent progress in developing physical dynamic adsorption models relating measured fluorescent dye intensities to underlying target mRNA concentration." @default.
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- W18085000 date "2007-06-14" @default.
- W18085000 modified "2023-09-25" @default.
- W18085000 title "Statistical Analysis and Physical Modelling of Oligonucleotide Microarrays" @default.
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- W18085000 doi "https://doi.org/10.1007/978-0-8176-4558-8_29" @default.
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