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- W180877488 abstract "The C. elegans histidyl-tRNA synthetase gene has been cloned and sequenced. The complete genomic sequence and most of the cDNA sequence of this gene is now determined. The gene size including flanking and coding regions is 2200 nucleotides. Three small introns (45-50 bp) are found to interrupt the open reading frame. The open reading frame translates to 523 amino acids. This putative protein sequence shows extensive homology with the human and yeast histidyl-tRNA synthetases. The C. elegans histidyl-tRNA synthetase gene maps on Linkage Group IV (LGIV) to 0.3 map units interval between mec-3 and lin-3 within the deficiency sDf2 in the unc-22 region. On the molecular map this gene falls in a region defined by four overlapping yacs in the unc-22 region. The histidyl-tRNA synthetase gene is a single copy gene. Hence, it is very likely that it encodes both the cytoplasmic and the mitochondrial histidyl-tRNA synthetases. It may also be tram-spliced since it contains a putative trans-splice site in its 5' untranslated region." @default.
- W180877488 created "2016-06-24" @default.
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- W180877488 date "1992-01-01" @default.
- W180877488 modified "2023-09-26" @default.
- W180877488 title "Cloning and characterization of the Caenorhabditis elegans histidyl-tRNA synthetase gene" @default.
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