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- W1809871539 abstract "Chloroquine increased the binding of 125I-labeled insulin to rat hepatoma cells (R-Y121B) at 4°C. The effect of chloroquine on insulin binding was amplified at 23°C, and a large increase in cell-associated radioactivity was observed. Scatchard analysis showed that chloroquine increased the affinity of insulin for cells at both 4°C and 23°C, and that this increase eventually caused the accumulation of insulin internalized by cells at 23°C." @default.
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- W1809871539 date "1987-01-01" @default.
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- W1809871539 title "Increase in Insulin Binding Affinity by Chloroquine in Cultured Rat Hepatoma Cells" @default.
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- W1809871539 doi "https://doi.org/10.1080/07435808709023662" @default.
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