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- W181041877 abstract "ABSTRACT This chapter describes representative examples of peptides and depsipeptides produced by plant pathogenic fungi, their biological and ecological roles, as well as potential application of current knowledge to agriculture and food production. Fungi are known to produce an enormous array of secondary metabolites, many of which have unknown function and bioactivity. Despite their incredible structural diversity, according to their basic biosynthetic precursors—their “building blocks”—these metabolites can be classified into four main groups: (1) acetyl coenzyme A and malonyl coenzyme A, which lead to the formation of polyketides; (2) mevalonic acid, which leads to synthesis of terpenoids and steroids; (3) shikimic acid, which leads to formation of shikimates and derivatives of aromatic amino acids, including some alkaloids; and (4) nonaromatic amino acids, including unusual amino acids, which lead to formation of alkaloids [ 4 ]. The last two categories comprise depsipeptides and peptides. Common investigation of secondary metabolites starts with their isolation, purification, and chemical structure elucidation. However, in many cases the low availability of metabolites—no longer an impediment to chemical structure determination—still poses constraints to an integrated understanding of fungal secondary metabolites. Nonetheless, it is well known that secondary metabolites have a variety of roles in fungi, including mediation of the interactions between fungi and plants, fungi and animals, and fungi and microorganisms. Although secondary metabolites of extremely diverse chemical structures have been isolated from fungi, this chapter describes only representative examples of peptides and depsipeptides produced by plant pathogenic fungi, their biological and ecological roles, and potential application of current knowledge to agriculture and food production." @default.
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- W181041877 date "2006-01-01" @default.
- W181041877 modified "2023-09-26" @default.
- W181041877 title "Peptides and Depsipeptides from Plant Pathogenic Fungi" @default.
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