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• W1810509997 abstract "The etiology of myalgic encephalomyelitis also known as chronic fatigue syndrome or ME/CFS has not been established. Controversies exist over whether it is an organic disease or a psychological disorder and even the existence of ME/CFS as a disease entity is sometimes denied. Suggested causal hypotheses have included psychosomatic disorders, infectious agents, immune dysfunctions, autoimmunity, metabolic disturbances, toxins and inherited genetic factors. Clinical, immunological and epidemiological evidence supports the hypothesis that: ME/CFS is an infectious disease; the causal pathogen persists in patients; the pathogen can be transmitted by casual contact; host factors determine susceptibility to the illness; and there is a population of healthy carriers, who may be able to shed the pathogen. ME/CFS is endemic globally as sporadic cases and occasional cluster outbreaks (epidemics). Cluster outbreaks imply an infectious agent. An abrupt flu-like onset resembling an infectious illness occurs in outbreak patients and many sporadic patients. Immune responses in sporadic patients resemble immune responses in other infectious diseases. Contagion is shown by finding secondary cases in outbreaks, and suggested by a higher prevalence of ME/CFS in sporadic patients’ genetically unrelated close contacts (spouses/partners) than the community. Abortive cases, sub-clinical cases, and carrier state individuals were found in outbreaks. The chronic phase of ME/CFS does not appear to be particularly infective. Some healthy patient-contacts show immune responses similar to patients’ immune responses, suggesting exposure to the same antigen (a pathogen). The chronicity of symptoms and of immune system changes and the occurrence of secondary cases suggest persistence of a causal pathogen. Risk factors which predispose to developing ME/CFS are: a close family member with ME/CFS; inherited genetic factors; female gender; age; rest/activity; previous exposure to stress or toxins; various infectious diseases preceding the onset of ME/CFS; and occupational exposure of health care professionals. The hypothesis implies that ME/CFS patients should not donate blood or tissue and usual precautions should be taken when handling patients’ blood and tissue. No known pathogen has been shown to cause ME/CFS. Confirmation of the hypothesis requires identification of a causal pathogen. Research should focus on a search for unknown and known pathogens. Finding a causal pathogen could assist with diagnosis; help find a biomarker; enable the development of anti-microbial treatments; suggest preventive measures; explain pathophysiological findings; and reassure patients about the validity of their symptoms." @default.
• W1810509997 created "2016-06-24" @default.
• W1810509997 creator A5023746220 @default.
• W1810509997 date "2015-12-01" @default.
• W1810509997 modified "2023-10-04" @default.
• W1810509997 title "Myalgic encephalomyelitis, chronic fatigue syndrome: An infectious disease" @default.
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• W1810509997 cites W1499533254 @default.
• W1810509997 cites W1806240087 @default.
• W1810509997 cites W1934388450 @default.
• W1810509997 cites W1970825432 @default.
• W1810509997 cites W1974098086 @default.
• W1810509997 cites W1974916205 @default.
• W1810509997 cites W1978978844 @default.
• W1810509997 cites W1982995518 @default.
• W1810509997 cites W1990310816 @default.
• W1810509997 cites W2012740861 @default.
• W1810509997 cites W2021748243 @default.
• W1810509997 cites W2023105134 @default.
• W1810509997 cites W2030464723 @default.
• W1810509997 cites W2033266000 @default.
• W1810509997 cites W2037103655 @default.
• W1810509997 cites W2042987550 @default.
• W1810509997 cites W2047830344 @default.
• W1810509997 cites W2053715625 @default.
• W1810509997 cites W2054969332 @default.
• W1810509997 cites W2055859925 @default.
• W1810509997 cites W2057746847 @default.
• W1810509997 cites W2058152745 @default.
• W1810509997 cites W2059470741 @default.
• W1810509997 cites W2069457638 @default.
• W1810509997 cites W2070222457 @default.
• W1810509997 cites W2070362655 @default.
• W1810509997 cites W2072649921 @default.
• W1810509997 cites W2073143853 @default.
• W1810509997 cites W2073673318 @default.
• W1810509997 cites W2077708137 @default.
• W1810509997 cites W2082082646 @default.
• W1810509997 cites W2084501255 @default.
• W1810509997 cites W2096399182 @default.
• W1810509997 cites W2098287790 @default.
• W1810509997 cites W2098566750 @default.
• W1810509997 cites W2102235987 @default.
• W1810509997 cites W21050205 @default.
• W1810509997 cites W2106406245 @default.
• W1810509997 cites W2108466384 @default.
• W1810509997 cites W2110408075 @default.
• W1810509997 cites W2112367760 @default.
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• W1810509997 cites W2115669202 @default.
• W1810509997 cites W2118518863 @default.
• W1810509997 cites W2121149906 @default.
• W1810509997 cites W2121629072 @default.
• W1810509997 cites W2122793115 @default.
• W1810509997 cites W2127800531 @default.
• W1810509997 cites W2130966426 @default.
• W1810509997 cites W2133259253 @default.
• W1810509997 cites W2138995305 @default.
• W1810509997 cites W2144543799 @default.
• W1810509997 cites W2148067363 @default.
• W1810509997 cites W2149522551 @default.
• W1810509997 cites W2149699306 @default.
• W1810509997 cites W2150274355 @default.
• W1810509997 cites W2155596333 @default.
• W1810509997 cites W2156371711 @default.
• W1810509997 cites W2158302852 @default.
• W1810509997 cites W2160675481 @default.
• W1810509997 cites W2161499392 @default.
• W1810509997 cites W2163778828 @default.
• W1810509997 cites W2167270466 @default.
• W1810509997 cites W2168833309 @default.
• W1810509997 cites W2312713765 @default.
• W1810509997 cites W2312773681 @default.
• W1810509997 cites W2313539267 @default.
• W1810509997 cites W2335742057 @default.
• W1810509997 cites W4244372946 @default.
• W1810509997 cites W4244690232 @default.
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• W1810509997 doi "https://doi.org/10.1016/j.mehy.2015.10.011" @default.
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• W1810509997 hasPublicationYear "2015" @default.
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