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• W1811461306 endingPage "92S" @default.
• W1811461306 startingPage "84S" @default.
• W1811461306 abstract "Several studies during the past 15 years have shown that antihypertensive therapy with different types of drugs can reduce microalbuminuria or clinical proteinuria and retard the progression toward end-stage renal failure. However, some authors reported disparate renal protective effects of different antihypertensive drugs in diabetic animals and humans. In an attempt to resolve the controversy surrounding this possibility, previously we reported a meta-analysis of published studies in diabetics with microalbuminuria or overt proteinuria treated with conventional agents, angiotensin-converting enzyme (ACE) inhibitors, or calcium antagonists (Ca2+ antagonists). Here we present an updated meta-analysis of published studies in diabetics with microalbuminuria or clinical proteinuria (UProt), treated during > or = 4 weeks with ACE inhibitors, Ca2+ antagonists, or conventional therapy (diuretic and/or beta-blocker). Despite similar blood pressure (BP) reductions, UProt tended to decrease more on ACE inhibitors (on average -45%) than on conventional therapy (on average -23%) or Ca2+ antagonists other than nifedipine (on average -35%); in contrast, UProt tended to increase slightly on nifedipine (on average 5%, P < .05). On the basis of multiple regression analysis, ACE inhibitor-induced UProt changes correlated with BP changes (r = 0.77, P < .00001), averaged -28% at zero BP change, and varied 1.5% for each percent BP change. On conventional therapy, UProt and BP changes also correlated (r = 0.62, P < .005), but UProt began to decrease only after a BP reduction of > 5% and the slope was steeper (4% UProt change per percent BP change) than on ACE inhibitors.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W1811461306 created "2016-06-24" @default.
• W1811461306 creator A5035782276 @default.
• W1811461306 creator A5047591330 @default.
• W1811461306 creator A5090072910 @default.
• W1811461306 date "1994-09-01" @default.
• W1811461306 modified "2023-10-15" @default.
• W1811461306 title "Comparative Study of the Effect of ACE-Inhibitors and Other Antihypertensive Agents on Proteinuria in Diabetic Patients" @default.
• W1811461306 cites W133712074 @default.
• W1811461306 cites W14579190 @default.
• W1811461306 cites W1508155198 @default.
• W1811461306 cites W1577825212 @default.
• W1811461306 cites W1955985073 @default.
• W1811461306 cites W1965476867 @default.
• W1811461306 cites W1965762279 @default.
• W1811461306 cites W1968002068 @default.
• W1811461306 cites W1969066393 @default.
• W1811461306 cites W1970864879 @default.
• W1811461306 cites W1972939258 @default.
• W1811461306 cites W1974752290 @default.
• W1811461306 cites W1974945920 @default.
• W1811461306 cites W1975169308 @default.
• W1811461306 cites W1975184389 @default.
• W1811461306 cites W1980221786 @default.
• W1811461306 cites W1980297088 @default.
• W1811461306 cites W1981848329 @default.
• W1811461306 cites W1982291941 @default.
• W1811461306 cites W1983956013 @default.
• W1811461306 cites W1985779699 @default.
• W1811461306 cites W1985999990 @default.
• W1811461306 cites W1986924251 @default.
• W1811461306 cites W1986926001 @default.
• W1811461306 cites W1989849146 @default.
• W1811461306 cites W1990246781 @default.
• W1811461306 cites W1991896678 @default.
• W1811461306 cites W1992573754 @default.
• W1811461306 cites W1995857827 @default.
• W1811461306 cites W1996485736 @default.
• W1811461306 cites W1996992946 @default.
• W1811461306 cites W1999686904 @default.
• W1811461306 cites W2001049748 @default.
• W1811461306 cites W2011738540 @default.
• W1811461306 cites W2013109933 @default.
• W1811461306 cites W2017948590 @default.
• W1811461306 cites W2022029572 @default.
• W1811461306 cites W2022553426 @default.
• W1811461306 cites W2026555733 @default.
• W1811461306 cites W2028919494 @default.
• W1811461306 cites W2030615738 @default.
• W1811461306 cites W2033905400 @default.
• W1811461306 cites W2034083626 @default.
• W1811461306 cites W2039217085 @default.
• W1811461306 cites W2043623132 @default.
• W1811461306 cites W2045261889 @default.
• W1811461306 cites W2046303127 @default.
• W1811461306 cites W2046649453 @default.
• W1811461306 cites W2047691371 @default.
• W1811461306 cites W2050608260 @default.
• W1811461306 cites W2051091083 @default.
• W1811461306 cites W2052608990 @default.
• W1811461306 cites W2053248115 @default.
• W1811461306 cites W2054790972 @default.
• W1811461306 cites W2058051475 @default.
• W1811461306 cites W2059571085 @default.
• W1811461306 cites W2062888334 @default.
• W1811461306 cites W2064893479 @default.
• W1811461306 cites W2067296920 @default.
• W1811461306 cites W2071731731 @default.
• W1811461306 cites W2071992196 @default.
• W1811461306 cites W2073935745 @default.
• W1811461306 cites W2080083732 @default.
• W1811461306 cites W2080937276 @default.
• W1811461306 cites W2080991684 @default.
• W1811461306 cites W2090579934 @default.
• W1811461306 cites W2090669358 @default.
• W1811461306 cites W2091163434 @default.
• W1811461306 cites W2094636160 @default.
• W1811461306 cites W2094997730 @default.
• W1811461306 cites W2103753742 @default.
• W1811461306 cites W2105746151 @default.
• W1811461306 cites W2114498807 @default.
• W1811461306 cites W2139480984 @default.
• W1811461306 cites W2143508846 @default.
• W1811461306 cites W2146103534 @default.
• W1811461306 cites W2148748683 @default.
• W1811461306 cites W2156663584 @default.
• W1811461306 cites W2163984863 @default.
• W1811461306 cites W2165817140 @default.
• W1811461306 cites W2167523756 @default.
• W1811461306 cites W2169664930 @default.
• W1811461306 cites W2219058493 @default.
• W1811461306 cites W2285619458 @default.
• W1811461306 cites W2313462151 @default.
• W1811461306 cites W2319365248 @default.
• W1811461306 cites W2330121013 @default.
• W1811461306 cites W2330783781 @default.
• W1811461306 cites W2395264365 @default.
• W1811461306 cites W2396051933 @default.

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