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• W1811517156 endingPage "e50" @default.
• W1811517156 startingPage "e34" @default.
• W1811517156 abstract "Abstract Background The modern management of acute non-variceal upper gastrointestinal bleeding is centred on endoscopy, with recourse to interventional radiology and surgery in refractory cases. The appropriate use of intervention to optimize outcomes is reviewed. Methods A literature search was undertaken of PubMed and the Cochrane Central Register of Controlled Trials between January 1990 and April 2013 using validated search terms (with restrictions) relevant to upper gastrointestinal bleeding. Results Appropriate and adequate resuscitation, and risk stratification using validated scores should be initiated at diagnosis. Coagulopathy should be corrected along with blood transfusions, aiming for an international normalized ratio of less than 2·5 to proceed with possible endoscopic haemostasis and a haemoglobin level of 70 g/l (excluding patients with severe bleeding or ischaemia). Prokinetics and proton pump inhibitors (PPIs) can be administered while awaiting endoscopy, although they do not affect rebleeding, surgery or mortality rates. Endoscopic haemostasis using thermal or mechanical therapies alone or in combination with injection should be used in all patients with high-risk stigmata (Forrest I–IIb) within 24 h of presentation (possibly within 12 h if there is severe bleeding), followed by a 72-h intravenous infusion of PPI that has been shown to decrease further rebleeding, surgery and mortality. A second attempt at endoscopic haemostasis is generally made in patients with rebleeding. Uncontrolled bleeding should be treated with targeted or empirical transcatheter arterial embolization. Surgical intervention is required in the event of failure of endoscopic and radiological measures. Secondary PPI prophylaxis when indicated and Helicobacter pylori eradication are necessary to decrease recurrent bleeding, keeping in mind the increased false-negative testing rates in the setting of acute bleeding. Conclusion An evidence-based approach with multidisciplinary collaboration is required to optimize outcomes of patients presenting with acute non-variceal upper gastrointestinal bleeding." @default.
• W1811517156 created "2016-06-24" @default.
• W1811517156 creator A5003717104 @default.
• W1811517156 creator A5025156152 @default.
• W1811517156 creator A5039769924 @default.
• W1811517156 creator A5051765373 @default.
• W1811517156 date "2013-11-26" @default.
• W1811517156 modified "2023-10-03" @default.
• W1811517156 title "Multidisciplinary management strategies for acute non-variceal upper gastrointestinal bleeding" @default.
• W1811517156 cites W106033831 @default.
• W1811517156 cites W127034668 @default.
• W1811517156 cites W1511326335 @default.
• W1811517156 cites W1542542721 @default.
• W1811517156 cites W1544506625 @default.
• W1811517156 cites W158216511 @default.
• W1811517156 cites W1613006575 @default.
• W1811517156 cites W1874038071 @default.
• W1811517156 cites W1902163979 @default.
• W1811517156 cites W1964314767 @default.
• W1811517156 cites W1965700064 @default.
• W1811517156 cites W1968867633 @default.
• W1811517156 cites W1969878364 @default.
• W1811517156 cites W1969940327 @default.
• W1811517156 cites W1970651248 @default.
• W1811517156 cites W1973332496 @default.
• W1811517156 cites W1976665359 @default.
• W1811517156 cites W1977112096 @default.
• W1811517156 cites W1978206138 @default.
• W1811517156 cites W1982903554 @default.
• W1811517156 cites W1986727655 @default.
• W1811517156 cites W1989242615 @default.
• W1811517156 cites W1992289774 @default.
• W1811517156 cites W1998803404 @default.
• W1811517156 cites W2001236620 @default.
• W1811517156 cites W2003333405 @default.
• W1811517156 cites W2003513238 @default.
• W1811517156 cites W2005951741 @default.
• W1811517156 cites W2006383546 @default.
• W1811517156 cites W2007631012 @default.
• W1811517156 cites W2007661163 @default.
• W1811517156 cites W2007694674 @default.
• W1811517156 cites W2008000582 @default.
• W1811517156 cites W2010475681 @default.
• W1811517156 cites W2013885198 @default.
• W1811517156 cites W2015566364 @default.
• W1811517156 cites W2016146901 @default.
• W1811517156 cites W2016802248 @default.
• W1811517156 cites W2016805852 @default.
• W1811517156 cites W2019794179 @default.
• W1811517156 cites W2022037434 @default.
• W1811517156 cites W2022421062 @default.
• W1811517156 cites W2022889473 @default.
• W1811517156 cites W2027154314 @default.
• W1811517156 cites W2027901856 @default.
• W1811517156 cites W2036677455 @default.
• W1811517156 cites W2039339158 @default.
• W1811517156 cites W2041284784 @default.
• W1811517156 cites W2043387284 @default.
• W1811517156 cites W2044767269 @default.
• W1811517156 cites W2044958189 @default.
• W1811517156 cites W2046301886 @default.
• W1811517156 cites W2046910626 @default.
• W1811517156 cites W2050616312 @default.
• W1811517156 cites W2052700582 @default.
• W1811517156 cites W2055354471 @default.
• W1811517156 cites W2056699051 @default.
• W1811517156 cites W2056997831 @default.
• W1811517156 cites W2059523739 @default.
• W1811517156 cites W2060995711 @default.
• W1811517156 cites W2061100128 @default.
• W1811517156 cites W2066628443 @default.
• W1811517156 cites W2066683918 @default.
• W1811517156 cites W2067264374 @default.
• W1811517156 cites W2072571958 @default.
• W1811517156 cites W2074697256 @default.
• W1811517156 cites W2075175323 @default.
• W1811517156 cites W2075644299 @default.
• W1811517156 cites W2078106122 @default.
• W1811517156 cites W2085242635 @default.
• W1811517156 cites W2086317534 @default.
• W1811517156 cites W2087425008 @default.
• W1811517156 cites W2089587835 @default.
• W1811517156 cites W2090610780 @default.
• W1811517156 cites W2100239503 @default.
• W1811517156 cites W2101433234 @default.
• W1811517156 cites W2108514030 @default.
• W1811517156 cites W2109525960 @default.
• W1811517156 cites W2112895275 @default.
• W1811517156 cites W2114222518 @default.
• W1811517156 cites W2114229368 @default.
• W1811517156 cites W2114614290 @default.
• W1811517156 cites W2119216632 @default.
• W1811517156 cites W2119853973 @default.
• W1811517156 cites W2120027412 @default.
• W1811517156 cites W2121314908 @default.
• W1811517156 cites W2126129345 @default.
• W1811517156 cites W2134651969 @default.
• W1811517156 cites W2135741427 @default.

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