Matches in SemOpenAlex for { <https://semopenalex.org/work/W181157777> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W181157777 abstract "Abstract : The dynamics of the host-parasite interaction after challenge with anthrax was studied by developing a procedure for survival experimentation that cannulated the thoracic and right lymph ducts. After aerosol challenge bacilli were observed in the lymph as early as nine and usually before 16 hours post-challenge and prior to observations of bacilli in the blood. Most bacilli are retained in the reticulo-endothelial system (RES) through an incubation period until the preterminal septicemia occurs. This stage is characterized by a logarithmic increase in numbers of bacilli and an increasing concentration of toxin. The doubling rate in the septicemic stage and number of bacilli/milliliter of blood at death are constants in each host species; however, immunization reduces the terminal number. Four different experimental approaches show that the rhesus monkey infected with anthrax dies of toxin. Two unevaluated tests give early indication of anthrax infection, namely cholinesterase inhibition and a cytoplasmic effect for guinea pig tissue cell sheets. A live vaccine as a booster following antigen results in a tremendous increase in resistance to;challenge. Antibiotic treatment with mice work shows clearly that penicillin is the antibiotic of choice. Streptomycin, aureomycin, and terramycin have value; chloramphenicol is of little value. A mathematical model of pathogenesis of anthrax has been developed." @default.
- W181157777 created "2016-06-24" @default.
- W181157777 creator A5026832825 @default.
- W181157777 creator A5026869402 @default.
- W181157777 creator A5041373377 @default.
- W181157777 creator A5053620204 @default.
- W181157777 creator A5055018081 @default.
- W181157777 date "1962-11-01" @default.
- W181157777 modified "2023-09-26" @default.
- W181157777 title "Pathogenesis of Anthrax - A Progress Report" @default.
- W181157777 hasPublicationYear "1962" @default.
- W181157777 type Work @default.
- W181157777 sameAs 181157777 @default.
- W181157777 citedByCount "1" @default.
- W181157777 crossrefType "journal-article" @default.
- W181157777 hasAuthorship W181157777A5026832825 @default.
- W181157777 hasAuthorship W181157777A5026869402 @default.
- W181157777 hasAuthorship W181157777A5041373377 @default.
- W181157777 hasAuthorship W181157777A5053620204 @default.
- W181157777 hasAuthorship W181157777A5055018081 @default.
- W181157777 hasConcept C142724271 @default.
- W181157777 hasConcept C159047783 @default.
- W181157777 hasConcept C203014093 @default.
- W181157777 hasConcept C2776870249 @default.
- W181157777 hasConcept C2779720271 @default.
- W181157777 hasConcept C2780239966 @default.
- W181157777 hasConcept C2780942790 @default.
- W181157777 hasConcept C501593827 @default.
- W181157777 hasConcept C523546767 @default.
- W181157777 hasConcept C54355233 @default.
- W181157777 hasConcept C71924100 @default.
- W181157777 hasConcept C86803240 @default.
- W181157777 hasConcept C89423630 @default.
- W181157777 hasConceptScore W181157777C142724271 @default.
- W181157777 hasConceptScore W181157777C159047783 @default.
- W181157777 hasConceptScore W181157777C203014093 @default.
- W181157777 hasConceptScore W181157777C2776870249 @default.
- W181157777 hasConceptScore W181157777C2779720271 @default.
- W181157777 hasConceptScore W181157777C2780239966 @default.
- W181157777 hasConceptScore W181157777C2780942790 @default.
- W181157777 hasConceptScore W181157777C501593827 @default.
- W181157777 hasConceptScore W181157777C523546767 @default.
- W181157777 hasConceptScore W181157777C54355233 @default.
- W181157777 hasConceptScore W181157777C71924100 @default.
- W181157777 hasConceptScore W181157777C86803240 @default.
- W181157777 hasConceptScore W181157777C89423630 @default.
- W181157777 hasLocation W1811577771 @default.
- W181157777 hasOpenAccess W181157777 @default.
- W181157777 hasPrimaryLocation W1811577771 @default.
- W181157777 hasRelatedWork W1898078764 @default.
- W181157777 hasRelatedWork W1975629780 @default.
- W181157777 hasRelatedWork W2012684708 @default.
- W181157777 hasRelatedWork W2115569211 @default.
- W181157777 hasRelatedWork W2142071288 @default.
- W181157777 hasRelatedWork W2142836431 @default.
- W181157777 hasRelatedWork W2146722736 @default.
- W181157777 hasRelatedWork W2149114563 @default.
- W181157777 hasRelatedWork W2161878707 @default.
- W181157777 hasRelatedWork W2166470557 @default.
- W181157777 hasRelatedWork W2174863803 @default.
- W181157777 hasRelatedWork W2328211115 @default.
- W181157777 hasRelatedWork W2401960092 @default.
- W181157777 hasRelatedWork W2558565552 @default.
- W181157777 hasRelatedWork W2589344389 @default.
- W181157777 hasRelatedWork W2593950564 @default.
- W181157777 hasRelatedWork W2755638713 @default.
- W181157777 hasRelatedWork W3087138963 @default.
- W181157777 hasRelatedWork W3132797510 @default.
- W181157777 hasRelatedWork W217225067 @default.
- W181157777 isParatext "false" @default.
- W181157777 isRetracted "false" @default.
- W181157777 magId "181157777" @default.
- W181157777 workType "article" @default.