FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1811700820> ?p ?o ?g. }

• W1811700820 endingPage "497" @default.
• W1811700820 startingPage "493" @default.
• W1811700820 abstract "The impact of several environmental and genetic factors on diabetes and its complications is well documented but there is an urgent need to understand more about genetic risk factors associated with this disease. The present study was aimed at examining the two single nucleotide polymorphisms (SNP) in intron 8 and exon 9 of the vitamin D receptor (VDR) gene in nephropathic and non-nephropathic type-2 diabetic patients. In this clinical study, peripheral blood samples were obtained from 100 type-2 diabetic patients, 100 nephropathic type-2 diabetic patients and 100 healthy controls. DNA was extracted and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was performed to examine two SNP polymorphisms within the VDR gene. Our results showed a significant difference in the Taq-1 evaluated genotypes of exon 9 in the VDR gene of diabetic individuals with (P=0.012) and without (P ≤ 0.001) nephropathy. Analysis of the Taq-1 evaluated alleles of nephropathic (P=0.917) and non-nephropathic (P=1.000) did not show a significant difference. We also evaluated the intron 8 Apa-1 alleles in patients with (P=0.480) and without nephropathy (P=0.543) and determined there were no differences between these groups. Our results also showed that the frequency of Apa-1 genotypes did not differ in nephropathic (P=0.224) and non-nephropathic (P=0.236) diabetic patients. Based on our results, it can be concluded that VDR and its functional polymorphism in exon 9 may play an important role in pathogenesis of type-2 diabetes and more investigations are required to clarify their role in nephropathy." @default.
• W1811700820 created "2016-06-24" @default.
• W1811700820 creator A5000240174 @default.
• W1811700820 creator A5000660647 @default.
• W1811700820 creator A5031067190 @default.
• W1811700820 creator A5048823259 @default.
• W1811700820 creator A5058242027 @default.
• W1811700820 creator A5058933195 @default.
• W1811700820 creator A5068356370 @default.
• W1811700820 date "2010-08-19" @default.
• W1811700820 modified "2023-10-15" @default.
• W1811700820 title "Polymorphisms within exon 9 but not intron 8 of the vitamin D receptor are associated with the nephropathic complication of type-2 diabetes" @default.
• W1811700820 cites W1971325542 @default.
• W1811700820 cites W1973740549 @default.
• W1811700820 cites W198103589 @default.
• W1811700820 cites W1981085663 @default.
• W1811700820 cites W1990076402 @default.
• W1811700820 cites W1991452120 @default.
• W1811700820 cites W1991827794 @default.
• W1811700820 cites W1995207587 @default.
• W1811700820 cites W2011040667 @default.
• W1811700820 cites W2026386906 @default.
• W1811700820 cites W2027638825 @default.
• W1811700820 cites W2029724839 @default.
• W1811700820 cites W2074322466 @default.
• W1811700820 cites W2091958703 @default.
• W1811700820 cites W2097065632 @default.
• W1811700820 cites W2112486322 @default.
• W1811700820 cites W2131030877 @default.
• W1811700820 cites W2138250844 @default.
• W1811700820 cites W2161276145 @default.
• W1811700820 cites W2168471060 @default.
• W1811700820 cites W2170288556 @default.
• W1811700820 cites W2171280161 @default.
• W1811700820 cites W96091253 @default.
• W1811700820 doi "https://doi.org/10.1111/j.1744-313x.2010.00953.x" @default.
• W1811700820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20727043" @default.
• W1811700820 hasPublicationYear "2010" @default.
• W1811700820 type Work @default.
• W1811700820 sameAs 1811700820 @default.
• W1811700820 citedByCount "36" @default.
• W1811700820 countsByYear W18117008202012 @default.
• W1811700820 countsByYear W18117008202013 @default.
• W1811700820 countsByYear W18117008202014 @default.
• W1811700820 countsByYear W18117008202015 @default.
• W1811700820 countsByYear W18117008202017 @default.
• W1811700820 countsByYear W18117008202018 @default.
• W1811700820 countsByYear W18117008202019 @default.
• W1811700820 countsByYear W18117008202021 @default.
• W1811700820 countsByYear W18117008202022 @default.
• W1811700820 crossrefType "journal-article" @default.
• W1811700820 hasAuthorship W1811700820A5000240174 @default.
• W1811700820 hasAuthorship W1811700820A5000660647 @default.
• W1811700820 hasAuthorship W1811700820A5031067190 @default.
• W1811700820 hasAuthorship W1811700820A5048823259 @default.
• W1811700820 hasAuthorship W1811700820A5058242027 @default.
• W1811700820 hasAuthorship W1811700820A5058933195 @default.
• W1811700820 hasAuthorship W1811700820A5068356370 @default.
• W1811700820 hasBestOaLocation W18117008202 @default.
• W1811700820 hasConcept C104317684 @default.
• W1811700820 hasConcept C124490489 @default.
• W1811700820 hasConcept C126322002 @default.
• W1811700820 hasConcept C134018914 @default.
• W1811700820 hasConcept C135763542 @default.
• W1811700820 hasConcept C139275648 @default.
• W1811700820 hasConcept C153209595 @default.
• W1811700820 hasConcept C168007829 @default.
• W1811700820 hasConcept C179639408 @default.
• W1811700820 hasConcept C180754005 @default.
• W1811700820 hasConcept C2777180221 @default.
• W1811700820 hasConcept C2779922275 @default.
• W1811700820 hasConcept C2781184683 @default.
• W1811700820 hasConcept C36823959 @default.
• W1811700820 hasConcept C54355233 @default.
• W1811700820 hasConcept C555293320 @default.
• W1811700820 hasConcept C71924100 @default.
• W1811700820 hasConcept C86803240 @default.
• W1811700820 hasConcept C94671646 @default.
• W1811700820 hasConceptScore W1811700820C104317684 @default.
• W1811700820 hasConceptScore W1811700820C124490489 @default.
• W1811700820 hasConceptScore W1811700820C126322002 @default.
• W1811700820 hasConceptScore W1811700820C134018914 @default.
• W1811700820 hasConceptScore W1811700820C135763542 @default.
• W1811700820 hasConceptScore W1811700820C139275648 @default.
• W1811700820 hasConceptScore W1811700820C153209595 @default.
• W1811700820 hasConceptScore W1811700820C168007829 @default.
• W1811700820 hasConceptScore W1811700820C179639408 @default.
• W1811700820 hasConceptScore W1811700820C180754005 @default.
• W1811700820 hasConceptScore W1811700820C2777180221 @default.
• W1811700820 hasConceptScore W1811700820C2779922275 @default.
• W1811700820 hasConceptScore W1811700820C2781184683 @default.
• W1811700820 hasConceptScore W1811700820C36823959 @default.
• W1811700820 hasConceptScore W1811700820C54355233 @default.
• W1811700820 hasConceptScore W1811700820C555293320 @default.
• W1811700820 hasConceptScore W1811700820C71924100 @default.
• W1811700820 hasConceptScore W1811700820C86803240 @default.
• W1811700820 hasConceptScore W1811700820C94671646 @default.
• W1811700820 hasIssue "6" @default.

• next