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- W1812022020 endingPage "28788" @default.
- W1812022020 startingPage "28788" @default.
- W1812022020 abstract "Porphyromonas gingivalis is considered a major pathogen in adult periodontitis and is also associated with multiple systemic diseases, for example, cardiovascular diseases. One of its most important virulence factors is invasion of host cells. The invasion process includes attachment, entry/internalization, trafficking, persistence, and exit. The present review discusses these processes related to P. gingivalis in cardiovascular cells and tissue. Although most P. gingivalis strains invade, the invasion capacity of strains and the mechanisms of invasion including intracellular trafficking among them differ. This is consistent with the fact that there are significant differences in the pathogenicity of P. gingivalis strains. P. gingivalis invasion mechanisms are also dependent on types of host cells. Although much is known about the invasion process of P. gingivalis, we still have little knowledge of its exit mechanisms. Nevertheless, it is intriguing that P. gingivalis can remain viable in human cardiovascular cells and atherosclerotic plaque and later exit and re-enter previously uninfected host cells." @default.
- W1812022020 created "2016-06-24" @default.
- W1812022020 creator A5034401865 @default.
- W1812022020 creator A5063541662 @default.
- W1812022020 date "2015-01-01" @default.
- W1812022020 modified "2023-09-27" @default.
- W1812022020 title "Invasion of <i>Porphyromonas gingivalis</i> strains into vascular cells and tissue" @default.
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- W1812022020 doi "https://doi.org/10.3402/jom.v7.28788" @default.
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