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- W1812510854 abstract "In the past several years, the effects of general anesthesia on cerebral circulation and metabolism have been studied at the University of Pennsylvania. During anesthesia the reactivity of the cerebral vasculature was retained during alterations of carbon dioxide tension. Furthermore, autoregulation to changes in arterial blood pressure was maintained except when profound vasodilatation was produced by the inhalation of cyclopropane. Finally, both cerebral circulation and oxygen consumption were influenced by anesthesia in the following way. With all anesthetics examined, cerebral blood flow decreased during light anesthesia and increased above control levels when anesthesia was deepened. Cerebral oxygen consumption appeared to decrease at all levels of anesthesia but was least depressed at moderate depths; cerebral oxygen utilization was most decreased when anesthesia was either light or very deep." @default.
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- W1812510854 date "1972-02-01" @default.
- W1812510854 modified "2023-10-14" @default.
- W1812510854 title "Effects of General Anesthesia on the Ratio of Cerebral Blood Flow to Cerebral Oxygen Utilization" @default.
- W1812510854 doi "https://doi.org/10.1016/s0012-3692(15)32690-8" @default.
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