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- W1815054832 abstract "Abstract Familial hypercholesterolaemia ( FH ) is a common genetic disorder affecting more than 8000 children and adolescents throughout A ustralia. It results in marked elevation in plasma low‐density lipoprotein cholesterol levels from birth that predisposes individuals to premature coronary heart disease in adult life. The majority of children and adolescents with FH are undiagnosed, as symptoms and signs only develop after decades of hypercholesterolaemia. Cascade screening of family members after detecting FH in an index case is an effective approach that allows the diagnosis of FH to be made in the young, before significant atherosclerosis develops. With the availability of effective therapies, mainly statins, paediatricians are ideally placed to improve the outcomes of this disorder by detecting and managing hypercholesterolaemia in childhood, thereby preventing premature coronary artery disease. We describe a new paediatric model of care for FH ." @default.
- W1815054832 created "2016-06-24" @default.
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- W1815054832 date "2012-12-16" @default.
- W1815054832 modified "2023-10-16" @default.
- W1815054832 title "Familial hypercholesterolaemia in children and adolescents: A new paediatric model of care" @default.
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- W1815054832 doi "https://doi.org/10.1111/jpc.12036" @default.
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