FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1818186442> ?p ?o ?g. }

• W1818186442 endingPage "712" @default.
• W1818186442 startingPage "705" @default.
• W1818186442 abstract "Research Article1 March 1991free access Translational control of transposition activity of the bacterial insertion sequence IS1. J. M. Escoubas J. M. Escoubas Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author M. F. Prère M. F. Prère Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author O. Fayet O. Fayet Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author I. Salvignol I. Salvignol Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author D. Galas D. Galas Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author D. Zerbib D. Zerbib Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author M. Chandler M. Chandler Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author J. M. Escoubas J. M. Escoubas Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author M. F. Prère M. F. Prère Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author O. Fayet O. Fayet Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author I. Salvignol I. Salvignol Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author D. Galas D. Galas Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author D. Zerbib D. Zerbib Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author M. Chandler M. Chandler Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. Search for more papers by this author Author Information J. M. Escoubas1, M. F. Prère1, O. Fayet1, I. Salvignol1, D. Galas1, D. Zerbib1 and M. Chandler1 1Centre de Recherche de Biochimie et Génétique Cellulaire du CNRS, Toulouse, France. The EMBO Journal (1991)10:705-712https://doi.org/10.1002/j.1460-2075.1991.tb08000.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info The experiments reported here provide strong evidence indicating that the transposition frequency of the bacterial insertion sequence IS1 is determined principally by two IS1-specified proteins. The first, InsA, was previously shown to bind to the ends of the element and to act as a repressor. We present both physical and genetic evidence which reveals that the second, the InsAB' transposase, is a fusion of InsA with the product of a downstream reading frame, InsB'. Synthesis of this protein occurs by a -1 frameshift between the insA and insB' frames. It requires the presence of an intact retroviral-like frameshift signal composed of an A6C motif and a downstream region able to form several alternative secondary structures. In vivo studies show that IS1 transposition activity depends on the relative rather than on the absolute levels of InsA and InsAB'. The ratio is determined primarily at the translational level by frameshifting and appears to be relatively insensitive to large variations in levels of transcription. This novel homeostatic control could therefore protect IS1 from activation as a consequence of insertion into active transcription units. Previous ArticleNext Article Volume 10Issue 31 March 1991In this issue RelatedDetailsLoading ..." @default.
• W1818186442 created "2016-06-24" @default.
• W1818186442 creator A5013235410 @default.
• W1818186442 creator A5027607291 @default.
• W1818186442 creator A5029641532 @default.
• W1818186442 creator A5051032780 @default.
• W1818186442 creator A5055985023 @default.
• W1818186442 creator A5076734819 @default.
• W1818186442 creator A5082862847 @default.
• W1818186442 date "1991-03-01" @default.
• W1818186442 modified "2023-09-30" @default.
• W1818186442 title "Translational control of transposition activity of the bacterial insertion sequence IS1." @default.
• W1818186442 cites W1486946238 @default.
• W1818186442 cites W1503716431 @default.
• W1818186442 cites W1507316687 @default.
• W1818186442 cites W1572344748 @default.
• W1818186442 cites W1873199501 @default.
• W1818186442 cites W1933230878 @default.
• W1818186442 cites W1966258844 @default.
• W1818186442 cites W1967164846 @default.
• W1818186442 cites W1973644872 @default.
• W1818186442 cites W1975993749 @default.
• W1818186442 cites W1984640298 @default.
• W1818186442 cites W1993343779 @default.
• W1818186442 cites W2002841189 @default.
• W1818186442 cites W2004312730 @default.
• W1818186442 cites W2008497514 @default.
• W1818186442 cites W2015315122 @default.
• W1818186442 cites W2015423007 @default.
• W1818186442 cites W2018289835 @default.
• W1818186442 cites W2018732451 @default.
• W1818186442 cites W2031092118 @default.
• W1818186442 cites W2040843640 @default.
• W1818186442 cites W2063832119 @default.
• W1818186442 cites W2065824991 @default.
• W1818186442 cites W2070936501 @default.
• W1818186442 cites W2078476938 @default.
• W1818186442 cites W2079671228 @default.
• W1818186442 cites W2080592353 @default.
• W1818186442 cites W2092974248 @default.
• W1818186442 cites W2096680495 @default.
• W1818186442 cites W2100837269 @default.
• W1818186442 cites W2102154371 @default.
• W1818186442 cites W2141653906 @default.
• W1818186442 cites W2151533084 @default.
• W1818186442 cites W2203207082 @default.
• W1818186442 cites W2413688039 @default.
• W1818186442 doi "https://doi.org/10.1002/j.1460-2075.1991.tb08000.x" @default.
• W1818186442 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/452705" @default.
• W1818186442 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1848178" @default.
• W1818186442 hasPublicationYear "1991" @default.
• W1818186442 type Work @default.
• W1818186442 sameAs 1818186442 @default.
• W1818186442 citedByCount "77" @default.
• W1818186442 countsByYear W18181864422013 @default.
• W1818186442 countsByYear W18181864422014 @default.
• W1818186442 countsByYear W18181864422016 @default.
• W1818186442 countsByYear W18181864422017 @default.
• W1818186442 countsByYear W18181864422021 @default.
• W1818186442 countsByYear W18181864422022 @default.
• W1818186442 crossrefType "journal-article" @default.
• W1818186442 hasAuthorship W1818186442A5013235410 @default.
• W1818186442 hasAuthorship W1818186442A5027607291 @default.
• W1818186442 hasAuthorship W1818186442A5029641532 @default.
• W1818186442 hasAuthorship W1818186442A5051032780 @default.
• W1818186442 hasAuthorship W1818186442A5055985023 @default.
• W1818186442 hasAuthorship W1818186442A5076734819 @default.
• W1818186442 hasAuthorship W1818186442A5082862847 @default.
• W1818186442 hasBestOaLocation W18181864423 @default.
• W1818186442 hasConcept C138885662 @default.
• W1818186442 hasConcept C15708023 @default.
• W1818186442 hasConcept C86803240 @default.
• W1818186442 hasConceptScore W1818186442C138885662 @default.
• W1818186442 hasConceptScore W1818186442C15708023 @default.
• W1818186442 hasConceptScore W1818186442C86803240 @default.
• W1818186442 hasIssue "3" @default.
• W1818186442 hasLocation W18181864421 @default.
• W1818186442 hasLocation W18181864422 @default.
• W1818186442 hasLocation W18181864423 @default.
• W1818186442 hasLocation W18181864424 @default.
• W1818186442 hasOpenAccess W1818186442 @default.
• W1818186442 hasPrimaryLocation W18181864421 @default.
• W1818186442 hasRelatedWork W1641042124 @default.
• W1818186442 hasRelatedWork W1990804418 @default.
• W1818186442 hasRelatedWork W1993764875 @default.
• W1818186442 hasRelatedWork W2013243191 @default.
• W1818186442 hasRelatedWork W2051339581 @default.
• W1818186442 hasRelatedWork W2082860237 @default.
• W1818186442 hasRelatedWork W2117258802 @default.
• W1818186442 hasRelatedWork W2130076355 @default.
• W1818186442 hasRelatedWork W2151865869 @default.
• W1818186442 hasRelatedWork W4234157524 @default.
• W1818186442 hasVolume "10" @default.
• W1818186442 isParatext "false" @default.
• W1818186442 isRetracted "false" @default.
• W1818186442 magId "1818186442" @default.
• W1818186442 workType "article" @default.