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- W1818746716 abstract "Cognitive behaviour therapy (CBT) and selective serotonin reuptake inhibitors are the most common treatments for pathological gambling (PG), but there are no published reports on combination treatment. This pilot study investigated the efficacy of CBT, paroxetine or combination in PG without co-morbidities. Thirty-four patients were randomly assigned to receive paroxetine, CBT+paroxetine, or CBT+placebo, for 16 weeks. Efficacy measures included the Yale Brown Obsessive Compulsive Scale modified for PG (PG-YBOCS), the Pathological Gambling Modification of the Clinical Global Impressions Scale (PG-CGI), and the Gambling Symptom Assessment Scale (G-SAS). Group improvement was comparable on the PG-YBOCS. However, at Week 16, the CBT groups showed significantly greater improvement on the PG-CGI, while G-SAS scores were significantly lower for CBT+MED than for the MED group. All three treatments improved pathological gambling behaviour. The combination may be more effective and may have the advantage of patient preference." @default.
- W1818746716 created "2016-06-24" @default.
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- W1818746716 date "2010-06-01" @default.
- W1818746716 modified "2023-09-26" @default.
- W1818746716 title "Paroxetine, Cognitive Behaviour Therapy or Combination in Pathological Gambling: A Pilot Investigation" @default.
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