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- W1819039565 abstract "During valine catabolism in muscle both 2-oxoisovalerate and 3-hydroxyisobutyrate can be released into the circulation. 3-Hydroxyisobutyrate is a good gluconeogenic substrate in isolated cortical tubules and hepatocytes. The maximal rate of gluconeogenesis from 3-hydroxyisobutyrate was greater than from 2-oxoisovalerate. We propose that 3-hydroxyisobutyrate is an inter-organ metabolite by which the gluconeogenic potential of valine, whose catabolism has been initiated in muscle, may be conserved." @default.
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- W1819039565 date "1986-12-15" @default.
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- W1819039565 title "Valine metabolism Gluconeogenesis from 3-hydroxyisobutyrate" @default.
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- W1819039565 doi "https://doi.org/10.1042/bj2400909" @default.
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