Matches in SemOpenAlex for { <https://semopenalex.org/work/W1820160109> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1820160109 endingPage "864" @default.
- W1820160109 startingPage "857" @default.
- W1820160109 abstract "We have carried out a comparison of KM and Vmax values for various primers in the polymerization reaction catalyzed by the HIV-1 RT. The affinity of RT for complementary d(pT)6 containing two different 5′-end pyranone derivatives was 2–3 orders of magnitude higher (KM = 3–15 nM) than that of d(pT)6 (KM = 12.6 mM). Oligodeoxynucleotides (ODNs) noncomplementary to poly(A) template were not elongated by RT. However, derivatives of d(CAGGTG) containing the 5′-terminal chromone and coumarin related groups were efficient primers showing KM (30–300 nM) and Vmax (75–93%) values comparable with that for d(pT)10 (800 nM; 100%). The [d(CAGGTG)]ddT ODN derivatives were effective inhibitors of RT. The primer function of derivatives of noncomplementary ODNs appears to be due to the additional interactions of their 5′-terminal groups with the enzyme tRNA-binding site." @default.
- W1820160109 created "2016-06-24" @default.
- W1820160109 creator A5021753245 @default.
- W1820160109 creator A5026737202 @default.
- W1820160109 creator A5032241496 @default.
- W1820160109 creator A5052444938 @default.
- W1820160109 creator A5053873069 @default.
- W1820160109 creator A5072530395 @default.
- W1820160109 creator A5073793923 @default.
- W1820160109 creator A5081504559 @default.
- W1820160109 creator A5084225070 @default.
- W1820160109 creator A5088123169 @default.
- W1820160109 date "1998-08-01" @default.
- W1820160109 modified "2023-10-18" @default.
- W1820160109 title "HIV-1 Reverse transcriptase is capable of elongating derivatives of sequence specific noncomplementary oligodeoxynucleotides" @default.
- W1820160109 cites W2144634347 @default.
- W1820160109 doi "https://doi.org/10.1002/iub.7510450502" @default.
- W1820160109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9739449" @default.
- W1820160109 hasPublicationYear "1998" @default.
- W1820160109 type Work @default.
- W1820160109 sameAs 1820160109 @default.
- W1820160109 citedByCount "2" @default.
- W1820160109 crossrefType "journal-article" @default.
- W1820160109 hasAuthorship W1820160109A5021753245 @default.
- W1820160109 hasAuthorship W1820160109A5026737202 @default.
- W1820160109 hasAuthorship W1820160109A5032241496 @default.
- W1820160109 hasAuthorship W1820160109A5052444938 @default.
- W1820160109 hasAuthorship W1820160109A5053873069 @default.
- W1820160109 hasAuthorship W1820160109A5072530395 @default.
- W1820160109 hasAuthorship W1820160109A5073793923 @default.
- W1820160109 hasAuthorship W1820160109A5081504559 @default.
- W1820160109 hasAuthorship W1820160109A5084225070 @default.
- W1820160109 hasAuthorship W1820160109A5088123169 @default.
- W1820160109 hasConcept C104317684 @default.
- W1820160109 hasConcept C156719811 @default.
- W1820160109 hasConcept C159047783 @default.
- W1820160109 hasConcept C178790620 @default.
- W1820160109 hasConcept C181199279 @default.
- W1820160109 hasConcept C185592680 @default.
- W1820160109 hasConcept C2777563447 @default.
- W1820160109 hasConcept C3013748606 @default.
- W1820160109 hasConcept C41183919 @default.
- W1820160109 hasConcept C55493867 @default.
- W1820160109 hasConcept C56856141 @default.
- W1820160109 hasConcept C67705224 @default.
- W1820160109 hasConcept C71240020 @default.
- W1820160109 hasConcept C86803240 @default.
- W1820160109 hasConceptScore W1820160109C104317684 @default.
- W1820160109 hasConceptScore W1820160109C156719811 @default.
- W1820160109 hasConceptScore W1820160109C159047783 @default.
- W1820160109 hasConceptScore W1820160109C178790620 @default.
- W1820160109 hasConceptScore W1820160109C181199279 @default.
- W1820160109 hasConceptScore W1820160109C185592680 @default.
- W1820160109 hasConceptScore W1820160109C2777563447 @default.
- W1820160109 hasConceptScore W1820160109C3013748606 @default.
- W1820160109 hasConceptScore W1820160109C41183919 @default.
- W1820160109 hasConceptScore W1820160109C55493867 @default.
- W1820160109 hasConceptScore W1820160109C56856141 @default.
- W1820160109 hasConceptScore W1820160109C67705224 @default.
- W1820160109 hasConceptScore W1820160109C71240020 @default.
- W1820160109 hasConceptScore W1820160109C86803240 @default.
- W1820160109 hasIssue "5" @default.
- W1820160109 hasLocation W18201601091 @default.
- W1820160109 hasLocation W18201601092 @default.
- W1820160109 hasOpenAccess W1820160109 @default.
- W1820160109 hasPrimaryLocation W18201601091 @default.
- W1820160109 hasRelatedWork W1495043192 @default.
- W1820160109 hasRelatedWork W1966152415 @default.
- W1820160109 hasRelatedWork W1970105686 @default.
- W1820160109 hasRelatedWork W2023644431 @default.
- W1820160109 hasRelatedWork W2042015157 @default.
- W1820160109 hasRelatedWork W2054221243 @default.
- W1820160109 hasRelatedWork W2073899392 @default.
- W1820160109 hasRelatedWork W2082042648 @default.
- W1820160109 hasRelatedWork W2333987642 @default.
- W1820160109 hasRelatedWork W3008382379 @default.
- W1820160109 hasVolume "45" @default.
- W1820160109 isParatext "false" @default.
- W1820160109 isRetracted "false" @default.
- W1820160109 magId "1820160109" @default.
- W1820160109 workType "article" @default.