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- W1820243661 abstract "Abstract The present study was undertaken to provide the foundation for development of genome‐scale resources for the fathead minnow ( Pimephales promelas ), an important model organism widely used in both aquatic toxicology research and regulatory testing. The authors report on the first sequencing and 2 draft assemblies for the reference genome of this species. Approximately 120× sequence coverage was achieved via Illumina sequencing of a combination of paired‐end, mate‐pair, and fosmid libraries. Evaluation and comparison of these assemblies demonstrate that they are of sufficient quality to be useful for genome‐enabled studies, with 418 of 458 (91%) conserved eukaryotic genes mapping to at least 1 of the assemblies. In addition to its immediate utility, the present work provides a strong foundation on which to build further refinements of a reference genome for the fathead minnow. Environ Toxicol Chem 2016;35:212–217. © 2015 SETAC" @default.
- W1820243661 created "2016-06-24" @default.
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- W1820243661 date "2015-10-29" @default.
- W1820243661 modified "2023-09-26" @default.
- W1820243661 title "Sequencing and de novo draft assemblies of a fathead minnow (<i>Pimephales promelas</i>) reference genome" @default.
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- W1820243661 doi "https://doi.org/10.1002/etc.3186" @default.
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