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• W1822009632 abstract "A series of bioactive bis(indolyl)methanes are synthesized by one-pot green reaction of indole with various substituted aldehydes by microwave irradiation under solvent free conditions. The antibacterial activity against Staphylococcus aureus and anti-inflammatory activity of the synthesized bis(indolyl)methanes are evaluated in vitro and compared to standard drugs tetracycline and diclofenac, respectively. The majority of the compounds showed good antibacterial and anti-inflammatory activity. Interestingly, compounds 3j, 3i, 3k and 3g exhibited much higher anti-inflammatory activity than the standard diclofenac drug and thus qualify for clinical trials to be used as an anti-inflammatory compound." @default.
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• W1822009632 date "2016-01-01" @default.
• W1822009632 modified "2023-10-12" @default.
• W1822009632 title "Synthesis, antibacterial and anti-inflammatory activity of bis(indolyl)methanes" @default.
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• W1822009632 doi "https://doi.org/10.1016/j.cclet.2015.08.012" @default.
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