Matches in SemOpenAlex for { <https://semopenalex.org/work/W1822473883> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1822473883 endingPage "154" @default.
- W1822473883 startingPage "139" @default.
- W1822473883 abstract "ABSTRACT Cultivation of limb-bone rudiments in medium containing various non-metabolizable or poorly metabolizable sugars caused vacuolation of the perichondrial and articular cells and was accompanied by an increased synthesis and profuse secretion of lysosomal enzymes. Experiments with [14C]dextran indicated that the cytoplasmic vacuolation was due not to a higher rate of endocytosis, but rather to an abnormally long persistence of the pinocytotic vacuoles. Meta-chromatic material was lost from the cartilage only in the immediate vicinity of the vacuolated articular chondrocytes and the amount of hexosamine and hydroxyproline released into the medium was not much increased. However, the hexosamine and hydroxyproline of the sucrosetreated rudiments was much more susceptible to extraction with neutral salt than those of paired controls. Sucrose taken up by the cells was liberated when the rudiments were returned to normal medium; this release, unlike the secretion of lysosomal enzymes, was unaffected by the presence of hydrocortisone. It is probable that the primary lysosomes, formed in the enlarged Golgi region, are the vehicles for the secretion of lysosomal enzymes. No appreciable amount of enzymic activity was released into the medium from rudiments grown in the presence of 0·08 M sucrose, before 36 h; at, or just before this time, however, a net increase in synthesis of enzyme was observed. The role of endocytosis in the resorption of skeletal matrix is discussed." @default.
- W1822473883 created "2016-06-24" @default.
- W1822473883 creator A5005540688 @default.
- W1822473883 creator A5079635683 @default.
- W1822473883 creator A5079956434 @default.
- W1822473883 date "1969-01-01" @default.
- W1822473883 modified "2023-10-18" @default.
- W1822473883 title "Endocytosis of Sugars in Embryonic Skeletal Tissues in Organ Culture" @default.
- W1822473883 cites W1581934034 @default.
- W1822473883 cites W1994113504 @default.
- W1822473883 cites W2015554386 @default.
- W1822473883 cites W2070476309 @default.
- W1822473883 cites W2414997889 @default.
- W1822473883 cites W2418535824 @default.
- W1822473883 cites W2897745919 @default.
- W1822473883 cites W85487559 @default.
- W1822473883 doi "https://doi.org/10.1242/jcs.4.1.139" @default.
- W1822473883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5777804" @default.
- W1822473883 hasPublicationYear "1969" @default.
- W1822473883 type Work @default.
- W1822473883 sameAs 1822473883 @default.
- W1822473883 citedByCount "66" @default.
- W1822473883 countsByYear W18224738832013 @default.
- W1822473883 countsByYear W18224738832018 @default.
- W1822473883 crossrefType "journal-article" @default.
- W1822473883 hasAuthorship W1822473883A5005540688 @default.
- W1822473883 hasAuthorship W1822473883A5079635683 @default.
- W1822473883 hasAuthorship W1822473883A5079956434 @default.
- W1822473883 hasConcept C102568950 @default.
- W1822473883 hasConcept C105702510 @default.
- W1822473883 hasConcept C119062480 @default.
- W1822473883 hasConcept C126322002 @default.
- W1822473883 hasConcept C1491633281 @default.
- W1822473883 hasConcept C181199279 @default.
- W1822473883 hasConcept C190062978 @default.
- W1822473883 hasConcept C202751555 @default.
- W1822473883 hasConcept C2779797417 @default.
- W1822473883 hasConcept C2780550940 @default.
- W1822473883 hasConcept C28005876 @default.
- W1822473883 hasConcept C28483552 @default.
- W1822473883 hasConcept C49039625 @default.
- W1822473883 hasConcept C55493867 @default.
- W1822473883 hasConcept C71924100 @default.
- W1822473883 hasConcept C86803240 @default.
- W1822473883 hasConcept C95444343 @default.
- W1822473883 hasConceptScore W1822473883C102568950 @default.
- W1822473883 hasConceptScore W1822473883C105702510 @default.
- W1822473883 hasConceptScore W1822473883C119062480 @default.
- W1822473883 hasConceptScore W1822473883C126322002 @default.
- W1822473883 hasConceptScore W1822473883C1491633281 @default.
- W1822473883 hasConceptScore W1822473883C181199279 @default.
- W1822473883 hasConceptScore W1822473883C190062978 @default.
- W1822473883 hasConceptScore W1822473883C202751555 @default.
- W1822473883 hasConceptScore W1822473883C2779797417 @default.
- W1822473883 hasConceptScore W1822473883C2780550940 @default.
- W1822473883 hasConceptScore W1822473883C28005876 @default.
- W1822473883 hasConceptScore W1822473883C28483552 @default.
- W1822473883 hasConceptScore W1822473883C49039625 @default.
- W1822473883 hasConceptScore W1822473883C55493867 @default.
- W1822473883 hasConceptScore W1822473883C71924100 @default.
- W1822473883 hasConceptScore W1822473883C86803240 @default.
- W1822473883 hasConceptScore W1822473883C95444343 @default.
- W1822473883 hasIssue "1" @default.
- W1822473883 hasLocation W18224738831 @default.
- W1822473883 hasLocation W18224738832 @default.
- W1822473883 hasOpenAccess W1822473883 @default.
- W1822473883 hasPrimaryLocation W18224738831 @default.
- W1822473883 hasRelatedWork W1578698280 @default.
- W1822473883 hasRelatedWork W2029012856 @default.
- W1822473883 hasRelatedWork W2040640578 @default.
- W1822473883 hasRelatedWork W2058452838 @default.
- W1822473883 hasRelatedWork W2094829070 @default.
- W1822473883 hasRelatedWork W2144071707 @default.
- W1822473883 hasRelatedWork W2417441064 @default.
- W1822473883 hasRelatedWork W2418821735 @default.
- W1822473883 hasRelatedWork W2434683782 @default.
- W1822473883 hasRelatedWork W3049621735 @default.
- W1822473883 hasVolume "4" @default.
- W1822473883 isParatext "false" @default.
- W1822473883 isRetracted "false" @default.
- W1822473883 magId "1822473883" @default.
- W1822473883 workType "article" @default.