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• W1823968245 abstract "Article1 April 1960OBESITY AND DIABETES: A REËVALUATIONS. K. FINEBERG, M.D., F.A.C.P.S. K. FINEBERG, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-4-750 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe recent popular acceptance of oral hypoglycemic agents necessitates renewed and heavy emphasis on the primary importance of controlling obesity in the management of concomitant diabetes mellitus. The use of these agents in the treatment of maturity-onset, mild diabetes, at least, is now firmly entrenched and widespread. Although they have proved their worth, in selected cases, by providing control of the disease while freeing significant numbers of this type of diabetic patient from the pain and inconvenience of daily insulin injections, there is still foremost among the dangers inherent in this long sought-for modality an enormous potentiality for abuse.Practical...Bibliography1. JoslinRootWhiteMarble EPHFPA: Treatment of diabetes mellitus, 8th Ed., 1946, Lea and Febiger, Philadelphia, p. 69. Google Scholar2. JoncasBissonnette FJ: Obesity and diabetes, Union méd. du Canada 86: 662-665 (June) 1957. MedlineGoogle Scholar3. NewburghConn LHJW: A new interpretation of hyperglycemia in middle-aged, obese persons, J. A. M. A. 112: 7 (Jan. 7) 1939. CrossrefGoogle Scholar4. Handelsman MB: Factors influencing the return of tolerance for glucose in middle-aged obese diabetics, Am. J. M. Sc. 208: 15 (July) 1944. CrossrefGoogle Scholar5. FetterDurkinDuncan FJKCC: Dietary versus insulin treatment of the obese diabetic patients, Am. J. M. Sc. 195: 781 (June) 1938. CrossrefGoogle Scholar6. OssermanDolger KEH: Obesity in diabetes: a study of therapy with anorexigenic drugs, Ann. Int. Med. 34: 72 (Jan.) 1951. LinkGoogle Scholar7. Conn JW: The prediabetic state in man, Diabetes 7: 347 (Sept.-Oct.) 1958. CrossrefMedlineGoogle Scholar8. Nathanson MH: The central action of beta-aminopropylbenzene (Benzedrine), J. A. M. A. 108: 528 (Feb. 13) 1937. CrossrefGoogle Scholar9. LessesMyerson MFA: Benzedrine sulfate as an aid in the treatment of obesity, New England J. Med. 218: 119 (Jan. 20) 1938. CrossrefGoogle Scholar10. StorzKirk HR: Über eine neue Blutdrucksteigernde Substanz, Deutsche med. Wchnschr. 63: 393 (Mar. 5) 1937. CrossrefGoogle Scholar11. DetrickMilikanModernThienes LERSFCH: On the pharmacology of phenylisopropylamine (Benzedrine), J. Pharmacol. and Exper. Therap. 60: 56 (May) 1937. Google Scholar12. GoodmanGilman LA: The pharmacological basis of therapeutics, 1st Ed., 1941, The Macmillan Co., New York, p. 438. Google Scholar13. GelvinMcGavackKenigsberg EPTHS: Phenmetrazine in the management of obesity, Am. J. Digest. Dis. 1: 155 (Apr.) 1956. CrossrefMedlineGoogle Scholar14. Ressler C: Treatment of obesity with phenmetrazine hydrochloride, a new anorexiant, J. A. M. A. 165: 135 (Sept. 14) 1957. CrossrefMedlineGoogle Scholar15. FeldmanAlbertonCraig RECL: Phenmetrazine hydrochloride, a clinical evaluation of a new anorectic agent, California Med. 87: 408 (Dec.) 1957. MedlineGoogle Scholar16. Barnes RH: Weight control—a practical office approach, J. A. M. A. 166: 898 (Feb. 22) 1958. CrossrefMedlineGoogle Scholar17. MelchionnaFerguson RF: Conference on therapy: treatment of obesity, Am. J. Med. 13: 478, 1952. CrossrefMedlineGoogle Scholar18. FazekasEhrmantrautKlen JFWRJ: A study of the effectiveness of certain anorexigenic agents, Am. J. M. Sc. 236: 692 (Dec.) 1958. CrossrefMedlineGoogle Scholar19. GoodmanGilman LA: The pharmacological basis of therapeutics, 2nd Ed., 1955, The Macmillan Co., New York, p. 521. Google Scholar20. HarrisIvySearle SCACLM: The mechanism of amphetamine-induced loss of weight, J. A. M. A. 134: 1468, 1947. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication June 29, 1959.From the Medical Service, Harlem Hospital, New York, N. Y.Requests for reprints should be addressed to S. K. Fineberg, M.D., 1056 Fifth Avenue, New York 28, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAn Appraisal of Anorexiants in the Treatment of Obesity*Orientierende ÜbersichtANOREXIGENIC DRUGS IN PERSPECTIVEOrientierende ÜbersichtAPPLICATION OF NEWER CONCEPTS IN DIABETES*Clinical Evaluation of a New Anorexigenic Drug, Aminoxaphen, in Obese Diabetics 1 April 1960Volume 52, Issue 4Page: 750-760KeywordsDiabetes mellitusHyperglycemiaHypoglycemicsIngestionInsulinMedical servicesObesityOverweightType 2 diabetes Issue Published: 1 April 1960 PDF downloadLoading ..." @default.
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