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- W1824150850 abstract "The concentrations of oxidized and reduced pyridine nucleotides in livers of caloric-restricted and ad libitum fed rats were measured. No persistent significant differences were found. The incorporation of acetate-C14 into lipids by liver slices from caloric-restricted rats was not significantly different from that of ad libitum controls. The in vivo incorporation of acetate-1-C14 into liver and carcass lipids by restricted rats was not significantly different from that of ad libitum controls. The conversion of acetate to CO2 by liver slices and by intact rats did not differ when caloric-restricted and ad libitum-fed rats were compared. It was suggested that the caloric-restriction adaptation involves a lower average turnover of fat as a result of cyclic variations in lipogenesis. This cyclic variation in lipogenesis may be a result of the pattern of food ingestion, a pattern characterized by periods of eating and fasting." @default.
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- W1824150850 date "1962-05-01" @default.
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- W1824150850 title "Some Relationships between Caloric Restriction and Body Weight in the Rat" @default.
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- W1824150850 doi "https://doi.org/10.1093/jn/77.1.91" @default.
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