FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1824175639> ?p ?o ?g. }

• W1824175639 abstract "The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. Furthermore, our aims were to evaluate our D-dimer method and to make comparisons with other D-dimer methods as with a new marker of coagulation, the APC-PCI complex. In addition, a cost effectiveness analysis was made of this diagnostic strategy.Material and methods: 357 outpatients with clinical suspicion of DVT were included in the clinical management study. The diagnostic workup included estimation of pre-test probability, D-dimer determination, objective imaging as well as 3 month clinical follow up of negative patients (Paper I). 350 plasma samples from the management study was used for comparison between two well established D-dimer methods and the APC-PCI complex (Paper II) and 311 plasma samples for the evaluation of two new D-dimer methods (Paper III). Direct and indirect costs were calculated for the tested diagnostic strategy and for two hypothetical strategies. A decision analysis was performed (Paper IV).Results and conclusions: One out of 110 patients categorized as having a low clinical probability in combination with a negative D-dimer test was diagnosed with DVT during follow up. About 30% of the patients do not need further investigation for DVT. The APC-PCI complex perform inferior to the D-dimer methods for the exclusion of DVT but slightly superior when indicating its presence. The AxSYM® and Innovance™ D-dimer assays perform well and in good agreement with the two well established assays with NPV´s of > 98% in the low clinical probability estimate (CP). Objective imaging in all patients was the least cost effective (€581) strategy, D-dimer screening of all patients before CP (€421) and CP in combination with D-Dimer testing only in patients with low CP (€406). Conclusion: the investigated diagnostic strategy is safe, result in more convenient and cost-effective care for patients." @default.
• W1824175639 created "2016-06-24" @default.
• W1824175639 creator A5049367949 @default.
• W1824175639 date "2010-01-01" @default.
• W1824175639 modified "2023-09-25" @default.
• W1824175639 title "Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis" @default.
• W1824175639 cites W1551336557 @default.
• W1824175639 cites W1590960449 @default.
• W1824175639 cites W1723148185 @default.
• W1824175639 cites W174419108 @default.
• W1824175639 cites W1759894762 @default.
• W1824175639 cites W1825221379 @default.
• W1824175639 cites W1850519358 @default.
• W1824175639 cites W1881100735 @default.
• W1824175639 cites W1892541075 @default.
• W1824175639 cites W1967125883 @default.
• W1824175639 cites W1968098708 @default.
• W1824175639 cites W1970116371 @default.
• W1824175639 cites W1970598617 @default.
• W1824175639 cites W1971228807 @default.
• W1824175639 cites W1971501970 @default.
• W1824175639 cites W1975547544 @default.
• W1824175639 cites W1975819811 @default.
• W1824175639 cites W1979157946 @default.
• W1824175639 cites W1980608787 @default.
• W1824175639 cites W1981156855 @default.
• W1824175639 cites W1983760732 @default.
• W1824175639 cites W1990916519 @default.
• W1824175639 cites W1994552143 @default.
• W1824175639 cites W1995033456 @default.
• W1824175639 cites W1995865724 @default.
• W1824175639 cites W1995871977 @default.
• W1824175639 cites W1999584733 @default.
• W1824175639 cites W2003632937 @default.
• W1824175639 cites W2008165833 @default.
• W1824175639 cites W2010944132 @default.
• W1824175639 cites W2013608204 @default.
• W1824175639 cites W2015865054 @default.
• W1824175639 cites W2015975446 @default.
• W1824175639 cites W2019095425 @default.
• W1824175639 cites W2021678294 @default.
• W1824175639 cites W2022388779 @default.
• W1824175639 cites W2022713742 @default.
• W1824175639 cites W2025651318 @default.
• W1824175639 cites W2026309267 @default.
• W1824175639 cites W2028987583 @default.
• W1824175639 cites W2029620746 @default.
• W1824175639 cites W2029716099 @default.
• W1824175639 cites W2030138838 @default.
• W1824175639 cites W2030228243 @default.
• W1824175639 cites W2031127066 @default.
• W1824175639 cites W2033582433 @default.
• W1824175639 cites W2035474793 @default.
• W1824175639 cites W2035824774 @default.
• W1824175639 cites W2038733492 @default.
• W1824175639 cites W2043306284 @default.
• W1824175639 cites W2046087461 @default.
• W1824175639 cites W2048386168 @default.
• W1824175639 cites W2049503062 @default.
• W1824175639 cites W2052535111 @default.
• W1824175639 cites W2060090185 @default.
• W1824175639 cites W2061025042 @default.
• W1824175639 cites W2063866881 @default.
• W1824175639 cites W2064553209 @default.
• W1824175639 cites W2064562336 @default.
• W1824175639 cites W2066681685 @default.
• W1824175639 cites W2067855848 @default.
• W1824175639 cites W2072829381 @default.
• W1824175639 cites W2072892867 @default.
• W1824175639 cites W2073116696 @default.
• W1824175639 cites W2075409030 @default.
• W1824175639 cites W2075666595 @default.
• W1824175639 cites W2077187666 @default.
• W1824175639 cites W2079447377 @default.
• W1824175639 cites W2080785051 @default.
• W1824175639 cites W2081540276 @default.
• W1824175639 cites W2084270771 @default.
• W1824175639 cites W2085129667 @default.
• W1824175639 cites W2092507063 @default.
• W1824175639 cites W2098105118 @default.
• W1824175639 cites W2103120830 @default.
• W1824175639 cites W2108127771 @default.
• W1824175639 cites W2109608564 @default.
• W1824175639 cites W2113405967 @default.
• W1824175639 cites W2113995738 @default.
• W1824175639 cites W2126286036 @default.
• W1824175639 cites W2126646660 @default.
• W1824175639 cites W2135573191 @default.
• W1824175639 cites W2135786030 @default.
• W1824175639 cites W2139088247 @default.
• W1824175639 cites W2141850575 @default.
• W1824175639 cites W2143859750 @default.
• W1824175639 cites W2146289187 @default.
• W1824175639 cites W2150121055 @default.
• W1824175639 cites W2151880534 @default.
• W1824175639 cites W2152717466 @default.
• W1824175639 cites W2156573757 @default.
• W1824175639 cites W2160022765 @default.
• W1824175639 cites W2160805842 @default.
• W1824175639 cites W2161114769 @default.

• next