FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1824191895> ?p ?o ?g. }

• W1824191895 endingPage "131" @default.
• W1824191895 startingPage "120" @default.
• W1824191895 abstract "Please cite this paper as: Nang et al. (2013) Live attenuated H5N1 vaccine with H9N2 internal genes protects chickens from infections by both Highly Pathogenic H5N1 and H9N2 Influenza Viruses. Influenza and Other Respiratory Viruses 7(2) 120–131. Background The highly pathogenic H5N1 and H9N2 influenza viruses are endemic in many countries around the world and have caused considerable economic loss to the poultry industry. Objectives We aimed to study whether a live attenuated H5N1 vaccine comprising internal genes from a cold‐adapted H9N2 influenza virus could protect chickens from infection by both H5N1 and H9N2 viruses. Methods We developed a cold‐adapted H9N2 vaccine virus expressing hemagglutinin and neuraminidase derived from the highly pathogenic H5N1 influenza virus using reverse genetics. Results and Conclusions Chickens immunized with the vaccine were protected from lethal infections with homologous and heterologous H5N1 or H9N2 influenza viruses. Specific antibody against H5N1 virus was detected up to 11 weeks after vaccination (the endpoint of this study). In vaccinated chickens, IgA and IgG antibody subtypes were induced in lung and intestinal tissue, and CD4+ and CD8+ T lymphocytes expressing interferon‐gamma were induced in the splenocytes. These data suggest that a live attenuated H5N1 vaccine with cold‐adapted H9N2 internal genes can protect chickens from infection with H5N1 and H9N2 influenza viruses by eliciting humoral and cellular immunity." @default.
• W1824191895 created "2016-06-24" @default.
• W1824191895 creator A5003286740 @default.
• W1824191895 creator A5022243140 @default.
• W1824191895 creator A5042384164 @default.
• W1824191895 creator A5075088268 @default.
• W1824191895 creator A5076625974 @default.
• W1824191895 creator A5077881315 @default.
• W1824191895 date "2012-04-09" @default.
• W1824191895 modified "2023-10-16" @default.
• W1824191895 title "Live attenuated H5N1 vaccine with H9N2 internal genes protects chickens from infections by both Highly Pathogenic H5N1 and H9N2 Influenza Viruses" @default.
• W1824191895 cites W1966361839 @default.
• W1824191895 cites W1972888626 @default.
• W1824191895 cites W1973077339 @default.
• W1824191895 cites W1977483997 @default.
• W1824191895 cites W1977991935 @default.
• W1824191895 cites W1989775123 @default.
• W1824191895 cites W1989975718 @default.
• W1824191895 cites W1999942453 @default.
• W1824191895 cites W2001624001 @default.
• W1824191895 cites W2020316997 @default.
• W1824191895 cites W2021693346 @default.
• W1824191895 cites W2022724574 @default.
• W1824191895 cites W2025691466 @default.
• W1824191895 cites W2029172350 @default.
• W1824191895 cites W2030895743 @default.
• W1824191895 cites W2038228839 @default.
• W1824191895 cites W2048121691 @default.
• W1824191895 cites W2049765201 @default.
• W1824191895 cites W2056124930 @default.
• W1824191895 cites W2057814651 @default.
• W1824191895 cites W2078246413 @default.
• W1824191895 cites W2083473920 @default.
• W1824191895 cites W2087480717 @default.
• W1824191895 cites W2088096486 @default.
• W1824191895 cites W2092097938 @default.
• W1824191895 cites W2094005687 @default.
• W1824191895 cites W2094279051 @default.
• W1824191895 cites W2101262013 @default.
• W1824191895 cites W2101954404 @default.
• W1824191895 cites W2102307607 @default.
• W1824191895 cites W2104498598 @default.
• W1824191895 cites W2106528995 @default.
• W1824191895 cites W2118967149 @default.
• W1824191895 cites W2121329353 @default.
• W1824191895 cites W2122242794 @default.
• W1824191895 cites W2126309815 @default.
• W1824191895 cites W2141139673 @default.
• W1824191895 cites W2146175559 @default.
• W1824191895 cites W2146335827 @default.
• W1824191895 cites W2147096864 @default.
• W1824191895 cites W2147651549 @default.
• W1824191895 cites W2148734478 @default.
• W1824191895 cites W2154403354 @default.
• W1824191895 cites W2163960578 @default.
• W1824191895 cites W2164890208 @default.
• W1824191895 cites W2168020376 @default.
• W1824191895 cites W4237236497 @default.
• W1824191895 cites W4300573951 @default.
• W1824191895 doi "https://doi.org/10.1111/j.1750-2659.2012.00363.x" @default.
• W1824191895 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5780756" @default.
• W1824191895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22487301" @default.
• W1824191895 hasPublicationYear "2012" @default.
• W1824191895 type Work @default.
• W1824191895 sameAs 1824191895 @default.
• W1824191895 citedByCount "11" @default.
• W1824191895 countsByYear W18241918952013 @default.
• W1824191895 countsByYear W18241918952014 @default.
• W1824191895 countsByYear W18241918952015 @default.
• W1824191895 countsByYear W18241918952016 @default.
• W1824191895 countsByYear W18241918952018 @default.
• W1824191895 countsByYear W18241918952019 @default.
• W1824191895 countsByYear W18241918952021 @default.
• W1824191895 countsByYear W18241918952022 @default.
• W1824191895 crossrefType "journal-article" @default.
• W1824191895 hasAuthorship W1824191895A5003286740 @default.
• W1824191895 hasAuthorship W1824191895A5022243140 @default.
• W1824191895 hasAuthorship W1824191895A5042384164 @default.
• W1824191895 hasAuthorship W1824191895A5075088268 @default.
• W1824191895 hasAuthorship W1824191895A5076625974 @default.
• W1824191895 hasAuthorship W1824191895A5077881315 @default.
• W1824191895 hasBestOaLocation W18241918951 @default.
• W1824191895 hasConcept C104317684 @default.
• W1824191895 hasConcept C133239900 @default.
• W1824191895 hasConcept C134164806 @default.
• W1824191895 hasConcept C142724271 @default.
• W1824191895 hasConcept C159047783 @default.
• W1824191895 hasConcept C22070199 @default.
• W1824191895 hasConcept C2522874641 @default.
• W1824191895 hasConcept C2777546802 @default.
• W1824191895 hasConcept C2778692840 @default.
• W1824191895 hasConcept C2779134260 @default.
• W1824191895 hasConcept C2780689484 @default.
• W1824191895 hasConcept C3008058167 @default.
• W1824191895 hasConcept C519248777 @default.
• W1824191895 hasConcept C524204448 @default.
• W1824191895 hasConcept C54355233 @default.
• W1824191895 hasConcept C54602769 @default.

• next