Matches in SemOpenAlex for { <https://semopenalex.org/work/W1824348259> ?p ?o ?g. }
- W1824348259 endingPage "1263" @default.
- W1824348259 startingPage "1250" @default.
- W1824348259 abstract "This study was undertaken to investigate the toxic effects of imidacloprid (IM) on male reproductive system and ameliorative effect of curcumin (CMN) in male Wistar rats. For this purpose, IM (45 and 90 mg/kg, body weight) and CMN (100 mg/kg, body weight) were administered orally to the rats either alone or in combinations for a period of 28 days. At the end of experiment, male reproductive toxicity parameters (total sperm count and sperm abnormalities), testosterone level, steroidal enzymatic activity [3β-hydroxysteroid dehydrogenase (3β-HSD) and 17β-HSD], and oxidative stress indicators were estimated in testis and plasma. IM treatments resulted in significant decrease (p < 0.05) in total epididymal sperm count, sperm motility, live sperm count, and increase (p < 0.05) in sperm abnormalities. Activities of gamma-glutamyl transpeptidase, lactate dehydrogenase-x, and sorbitol dehydrogenase were significantly increased (p < 0.05), while, 3β-HSD and 17β-HSD enzymatic activity along with testosterone concentration in testis and plasma were decreased significantly (p < 0.05) in IM-treated rats. IM exposure resulted in significant increase (p < 0.05) in LPO and decrease (p < 0.05) in GSH level along with decreased activities of CAT, SOD, GPx, and GST. IM-treated rats showed histopathological alterations in testis and epididymis. However, the reproductive toxicity parameters, oxidative stress indicators, and histopathological changes were minimized and functional restorations were noticed by co-administration of CMN in IM-treated rats. The results of this study suggest that IM-induced male reproductive toxic effects could be ameliorated by CMN supplementation. © 2015 Wiley Periodicals, Inc. Environ Toxicol 31: 1250–1263, 2016." @default.
- W1824348259 created "2016-06-24" @default.
- W1824348259 creator A5019408279 @default.
- W1824348259 creator A5028554949 @default.
- W1824348259 creator A5030895743 @default.
- W1824348259 creator A5064574894 @default.
- W1824348259 creator A5065107747 @default.
- W1824348259 creator A5079041374 @default.
- W1824348259 creator A5082388190 @default.
- W1824348259 date "2015-03-10" @default.
- W1824348259 modified "2023-10-05" @default.
- W1824348259 title "Evaluation of ameliorative effect of curcumin on imidacloprid-induced male reproductive toxicity in wistar rats" @default.
- W1824348259 cites W1481433938 @default.
- W1824348259 cites W1495384773 @default.
- W1824348259 cites W1528655921 @default.
- W1824348259 cites W1581414347 @default.
- W1824348259 cites W1775749144 @default.
- W1824348259 cites W1815255263 @default.
- W1824348259 cites W1888597759 @default.
- W1824348259 cites W1923523130 @default.
- W1824348259 cites W1967603833 @default.
- W1824348259 cites W1968012988 @default.
- W1824348259 cites W1968916176 @default.
- W1824348259 cites W1969272036 @default.
- W1824348259 cites W1972011876 @default.
- W1824348259 cites W1974368836 @default.
- W1824348259 cites W1975108157 @default.
- W1824348259 cites W1979589658 @default.
- W1824348259 cites W1980941943 @default.
- W1824348259 cites W1983310681 @default.
- W1824348259 cites W1983606361 @default.
- W1824348259 cites W1983646655 @default.
- W1824348259 cites W1984912857 @default.
- W1824348259 cites W1985945529 @default.
- W1824348259 cites W1987510808 @default.
- W1824348259 cites W1987987034 @default.
- W1824348259 cites W1990196591 @default.
- W1824348259 cites W1991327193 @default.
- W1824348259 cites W1993155998 @default.
- W1824348259 cites W1994070358 @default.
- W1824348259 cites W1994193544 @default.
- W1824348259 cites W2000332894 @default.
- W1824348259 cites W2001934317 @default.
- W1824348259 cites W2002311345 @default.
- W1824348259 cites W2003432897 @default.
- W1824348259 cites W2003706186 @default.
- W1824348259 cites W2003874630 @default.
- W1824348259 cites W2010413196 @default.
- W1824348259 cites W2011844120 @default.
- W1824348259 cites W2027549997 @default.
- W1824348259 cites W2029044261 @default.
- W1824348259 cites W2029114428 @default.
- W1824348259 cites W2038526929 @default.
- W1824348259 cites W2048747281 @default.
- W1824348259 cites W2054603877 @default.
- W1824348259 cites W2060545985 @default.
- W1824348259 cites W2060804956 @default.
- W1824348259 cites W2061566733 @default.
- W1824348259 cites W2063576996 @default.
- W1824348259 cites W2063751985 @default.
- W1824348259 cites W2064285785 @default.
- W1824348259 cites W2066733581 @default.
- W1824348259 cites W2069468086 @default.
- W1824348259 cites W2069473589 @default.
- W1824348259 cites W2077595642 @default.
- W1824348259 cites W2081651087 @default.
- W1824348259 cites W2083575893 @default.
- W1824348259 cites W2083747309 @default.
- W1824348259 cites W2086486239 @default.
- W1824348259 cites W2088146806 @default.
- W1824348259 cites W2088352865 @default.
- W1824348259 cites W2093773915 @default.
- W1824348259 cites W2094661911 @default.
- W1824348259 cites W2098341809 @default.
- W1824348259 cites W2103122715 @default.
- W1824348259 cites W2110750496 @default.
- W1824348259 cites W2114964972 @default.
- W1824348259 cites W2127897247 @default.
- W1824348259 cites W2130213300 @default.
- W1824348259 cites W2130614519 @default.
- W1824348259 cites W2131357228 @default.
- W1824348259 cites W2131813131 @default.
- W1824348259 cites W2132826785 @default.
- W1824348259 cites W2141515673 @default.
- W1824348259 cites W2149891144 @default.
- W1824348259 cites W2153361384 @default.
- W1824348259 cites W2159459465 @default.
- W1824348259 cites W2171423639 @default.
- W1824348259 cites W2319010121 @default.
- W1824348259 cites W2327823129 @default.
- W1824348259 cites W2399629773 @default.
- W1824348259 cites W4241518893 @default.
- W1824348259 doi "https://doi.org/10.1002/tox.22132" @default.
- W1824348259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25758541" @default.
- W1824348259 hasPublicationYear "2015" @default.
- W1824348259 type Work @default.
- W1824348259 sameAs 1824348259 @default.
- W1824348259 citedByCount "60" @default.