Matches in SemOpenAlex for { <https://semopenalex.org/work/W1824585952> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1824585952 endingPage "1266" @default.
- W1824585952 startingPage "1252" @default.
- W1824585952 abstract "The temporal sequence of axon-Schwann cell interaction during regeneration is examined in cat tibial nerves surgically denervated for 8 weeks and, subsequently, coated to a freshly severed peroneal nerve for 3 weeks. Prior to association with regenerating axons, Schwann cells resident in denervated and reinnervated stumps failed to synthesize proteins co-migrant with P0, P1, and P2 myelin proteins in contrast to normal nerves. Axonal association with Schwann cells stimulated synthesis of amino acid-labeled proteins co-migrating with myelin-specific proteins prior to elaboration of myelin lamellae. Radioactivity from these peaks was precipitated by antibodies raised against myelin-specific proteins. The synthesis of P1 and P2 proteins was evident before P0 synthesis in reinnervated stumps. Immunocytochemical staining with antibody to P0, P1, P2, and myelin- associated glycoprotein (MAG) appeared only after myelin lamellae had been formed. These data suggest that Schwann cells: (a) synthesize proteins co-migrant with P1, P2, P0, and MAG in normal cat nerves; (b) cease detectable manufacture of these proteins after axonal loss; (c) regain their capacity to synthesize these proteins upon re- establishment of axonal association; and (d) during regeneration, express the synthesis of P1 and P2 before that of P0." @default.
- W1824585952 created "2016-06-24" @default.
- W1824585952 creator A5010386883 @default.
- W1824585952 creator A5049791449 @default.
- W1824585952 creator A5057865874 @default.
- W1824585952 creator A5083220349 @default.
- W1824585952 date "1982-09-01" @default.
- W1824585952 modified "2023-09-26" @default.
- W1824585952 title "Studies on the control of myelinogenesis. IV. Neuronal induction of Schwann cell myelin-specific protein synthesis during nerve fiber regeneration" @default.
- W1824585952 cites W1544849627 @default.
- W1824585952 cites W1968138628 @default.
- W1824585952 cites W1982043997 @default.
- W1824585952 cites W2005486264 @default.
- W1824585952 cites W2005597408 @default.
- W1824585952 cites W2009052046 @default.
- W1824585952 cites W2018747295 @default.
- W1824585952 cites W2026730273 @default.
- W1824585952 cites W2027866675 @default.
- W1824585952 cites W2032552530 @default.
- W1824585952 cites W2034088005 @default.
- W1824585952 cites W2047025292 @default.
- W1824585952 cites W2061888569 @default.
- W1824585952 cites W2065965177 @default.
- W1824585952 cites W2072841951 @default.
- W1824585952 cites W2119216843 @default.
- W1824585952 cites W2122283078 @default.
- W1824585952 doi "https://doi.org/10.1523/jneurosci.02-09-01252.1982" @default.
- W1824585952 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6564322" @default.
- W1824585952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6181233" @default.
- W1824585952 hasPublicationYear "1982" @default.
- W1824585952 type Work @default.
- W1824585952 sameAs 1824585952 @default.
- W1824585952 citedByCount "74" @default.
- W1824585952 crossrefType "journal-article" @default.
- W1824585952 hasAuthorship W1824585952A5010386883 @default.
- W1824585952 hasAuthorship W1824585952A5049791449 @default.
- W1824585952 hasAuthorship W1824585952A5057865874 @default.
- W1824585952 hasAuthorship W1824585952A5083220349 @default.
- W1824585952 hasBestOaLocation W18245859521 @default.
- W1824585952 hasConcept C108625454 @default.
- W1824585952 hasConcept C153911025 @default.
- W1824585952 hasConcept C169760540 @default.
- W1824585952 hasConcept C171056886 @default.
- W1824585952 hasConcept C2777004073 @default.
- W1824585952 hasConcept C2778609137 @default.
- W1824585952 hasConcept C2779530196 @default.
- W1824585952 hasConcept C2780064007 @default.
- W1824585952 hasConcept C2780876595 @default.
- W1824585952 hasConcept C3017789999 @default.
- W1824585952 hasConcept C529278444 @default.
- W1824585952 hasConcept C64348767 @default.
- W1824585952 hasConcept C8162170 @default.
- W1824585952 hasConcept C86803240 @default.
- W1824585952 hasConcept C95444343 @default.
- W1824585952 hasConceptScore W1824585952C108625454 @default.
- W1824585952 hasConceptScore W1824585952C153911025 @default.
- W1824585952 hasConceptScore W1824585952C169760540 @default.
- W1824585952 hasConceptScore W1824585952C171056886 @default.
- W1824585952 hasConceptScore W1824585952C2777004073 @default.
- W1824585952 hasConceptScore W1824585952C2778609137 @default.
- W1824585952 hasConceptScore W1824585952C2779530196 @default.
- W1824585952 hasConceptScore W1824585952C2780064007 @default.
- W1824585952 hasConceptScore W1824585952C2780876595 @default.
- W1824585952 hasConceptScore W1824585952C3017789999 @default.
- W1824585952 hasConceptScore W1824585952C529278444 @default.
- W1824585952 hasConceptScore W1824585952C64348767 @default.
- W1824585952 hasConceptScore W1824585952C8162170 @default.
- W1824585952 hasConceptScore W1824585952C86803240 @default.
- W1824585952 hasConceptScore W1824585952C95444343 @default.
- W1824585952 hasIssue "9" @default.
- W1824585952 hasLocation W18245859521 @default.
- W1824585952 hasLocation W18245859522 @default.
- W1824585952 hasLocation W18245859523 @default.
- W1824585952 hasLocation W18245859524 @default.
- W1824585952 hasLocation W18245859525 @default.
- W1824585952 hasOpenAccess W1824585952 @default.
- W1824585952 hasPrimaryLocation W18245859521 @default.
- W1824585952 hasRelatedWork W1494592395 @default.
- W1824585952 hasRelatedWork W154909546 @default.
- W1824585952 hasRelatedWork W1824585952 @default.
- W1824585952 hasRelatedWork W2027240637 @default.
- W1824585952 hasRelatedWork W2040199078 @default.
- W1824585952 hasRelatedWork W2060190303 @default.
- W1824585952 hasRelatedWork W2075280039 @default.
- W1824585952 hasRelatedWork W2080398164 @default.
- W1824585952 hasRelatedWork W2085893808 @default.
- W1824585952 hasRelatedWork W2387084393 @default.
- W1824585952 hasVolume "2" @default.
- W1824585952 isParatext "false" @default.
- W1824585952 isRetracted "false" @default.
- W1824585952 magId "1824585952" @default.
- W1824585952 workType "article" @default.