Matches in SemOpenAlex for { <https://semopenalex.org/work/W1825288200> ?p ?o ?g. }
- W1825288200 endingPage "443" @default.
- W1825288200 startingPage "437" @default.
- W1825288200 abstract "The putative involvement of the cerebellum in the pathogenesis of cortical myoclonic syndromes has been long hypothesized, as neuropathological changes in patients with cortical myoclonus have most commonly been found in the cerebellum rather than in the suspected culprit, the primary somatosensory cortex. A model of increased cortical excitability due to loss of cerebellar inhibitory control via cerebello-thalamo-cortical connections has been proposed, but evidence remains equivocal. Here, we explore this hypothesis by examining syndromes that present with cortical myoclonus and ataxia. We first describe common clinical characteristics and underlying neuropathology. We critically view information on cerebellar physiology with regard to motorcortical output and compare findings between hypothesized and reported neurophysiological changes in conditions with cortical myoclonus and ataxia. We synthesize knowledge and focus on neurochemical changes in these conditions. Finally, we propose that the combination of alterations in inhibitory neurotransmission and the presence of cerebellar pathology are important elements in the pathogenesis of cortical myoclonus." @default.
- W1825288200 created "2016-06-24" @default.
- W1825288200 creator A5013166591 @default.
- W1825288200 creator A5014214000 @default.
- W1825288200 creator A5019155615 @default.
- W1825288200 creator A5025426792 @default.
- W1825288200 creator A5078261834 @default.
- W1825288200 creator A5088964079 @default.
- W1825288200 date "2014-03-14" @default.
- W1825288200 modified "2023-10-18" @default.
- W1825288200 title "The role of the cerebellum in the pathogenesis of cortical myoclonus" @default.
- W1825288200 cites W1597203818 @default.
- W1825288200 cites W1631789313 @default.
- W1825288200 cites W1963618508 @default.
- W1825288200 cites W1964330619 @default.
- W1825288200 cites W1964512750 @default.
- W1825288200 cites W1971129496 @default.
- W1825288200 cites W1973591639 @default.
- W1825288200 cites W1974947948 @default.
- W1825288200 cites W1993914606 @default.
- W1825288200 cites W1994288348 @default.
- W1825288200 cites W1996744439 @default.
- W1825288200 cites W1997622565 @default.
- W1825288200 cites W1998579485 @default.
- W1825288200 cites W1999702809 @default.
- W1825288200 cites W2004995700 @default.
- W1825288200 cites W2006281673 @default.
- W1825288200 cites W2015585455 @default.
- W1825288200 cites W2016052887 @default.
- W1825288200 cites W2018013903 @default.
- W1825288200 cites W2018882057 @default.
- W1825288200 cites W2019232135 @default.
- W1825288200 cites W2026348583 @default.
- W1825288200 cites W2030434347 @default.
- W1825288200 cites W2031180066 @default.
- W1825288200 cites W2031508186 @default.
- W1825288200 cites W2032763046 @default.
- W1825288200 cites W2038976330 @default.
- W1825288200 cites W2041035785 @default.
- W1825288200 cites W2041293133 @default.
- W1825288200 cites W2041790352 @default.
- W1825288200 cites W2041989893 @default.
- W1825288200 cites W2044246406 @default.
- W1825288200 cites W2054991490 @default.
- W1825288200 cites W2059879344 @default.
- W1825288200 cites W2060441085 @default.
- W1825288200 cites W2060957171 @default.
- W1825288200 cites W2065589509 @default.
- W1825288200 cites W2066470075 @default.
- W1825288200 cites W2068081016 @default.
- W1825288200 cites W2070852284 @default.
- W1825288200 cites W2075127960 @default.
- W1825288200 cites W2075801228 @default.
- W1825288200 cites W2075852657 @default.
- W1825288200 cites W2077502989 @default.
- W1825288200 cites W2078875154 @default.
- W1825288200 cites W2080669639 @default.
- W1825288200 cites W2082435953 @default.
- W1825288200 cites W2082467230 @default.
- W1825288200 cites W2082608110 @default.
- W1825288200 cites W2084746602 @default.
- W1825288200 cites W2085240659 @default.
- W1825288200 cites W2086692545 @default.
- W1825288200 cites W2092226919 @default.
- W1825288200 cites W2092338449 @default.
- W1825288200 cites W2098284652 @default.
- W1825288200 cites W2098426930 @default.
- W1825288200 cites W2098957660 @default.
- W1825288200 cites W2101172138 @default.
- W1825288200 cites W2104176252 @default.
- W1825288200 cites W2117435431 @default.
- W1825288200 cites W2117951410 @default.
- W1825288200 cites W2119989997 @default.
- W1825288200 cites W2120861193 @default.
- W1825288200 cites W2129469919 @default.
- W1825288200 cites W2132477219 @default.
- W1825288200 cites W2134766199 @default.
- W1825288200 cites W2137918350 @default.
- W1825288200 cites W2138788991 @default.
- W1825288200 cites W2152669364 @default.
- W1825288200 cites W2155299862 @default.
- W1825288200 cites W2156562602 @default.
- W1825288200 cites W2156746902 @default.
- W1825288200 cites W2157680277 @default.
- W1825288200 cites W2163680705 @default.
- W1825288200 cites W2168529864 @default.
- W1825288200 cites W2169407232 @default.
- W1825288200 cites W2287372120 @default.
- W1825288200 cites W4211148593 @default.
- W1825288200 cites W4234012928 @default.
- W1825288200 cites W96842918 @default.
- W1825288200 doi "https://doi.org/10.1002/mds.25867" @default.
- W1825288200 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24634361" @default.
- W1825288200 hasPublicationYear "2014" @default.
- W1825288200 type Work @default.
- W1825288200 sameAs 1825288200 @default.
- W1825288200 citedByCount "40" @default.
- W1825288200 countsByYear W18252882002015 @default.