FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1825599478> ?p ?o ?g. }

• W1825599478 endingPage "7e" @default.
• W1825599478 startingPage "112e" @default.
• W1825599478 abstract "APOBEC3B is a deaminase that possesses DNA C-to-T editing activity. A recent report showed that APOBEC3B mRNA was overexpressed in breast cancer and that its expression was responsible for the high C-to-T mutation spectrum in breast cancer, suggesting that APOBEC3B could serve as a source for producing mutations. To see whether APOBEC3B is overexpressed in other common cancers at the protein level, we investigated APOBEC3 protein expression in 100 gastric, 103 colorectal and 107 prostate cancer tissues as well as in 10 breast cancers by immunohistochemistry using antibody that could detect APOBEC3B, APOBEC3F and APOBEC3D proteins.In the cancers, APOBEC3 expression was detected in 100% of breast cancers, 67% of gastric, 84% of colorectal and 67% of prostate cancer. Also, it was expressed in 100% of normal breast, 90% of normal stomach, 82% of normal colon and 93% of normal prostate tissues. In contrast to earlier data that showed an increased APOBEC3B expression in breast cancer cells compared to normal breast cells, APOBEC3 expression in cancers was lower than in normal tissues (gastric and prostate cancer) or was not different from normal tissues (colorectal and breast cancer). There was no significant association of APOBEC3 expression with clinocopathological parameters, including histology, metastasis and stage.Our data indicate that APOBEC3 overexpression might not be restricted to specific cancer types. Also, APOBEC3 expression in many normal epithelial cells suggests that there might be a mutation unrelated function of APOBEC3 in the normal cells." @default.
• W1825599478 created "2016-06-24" @default.
• W1825599478 creator A5005078397 @default.
• W1825599478 creator A5015567806 @default.
• W1825599478 creator A5030743761 @default.
• W1825599478 creator A5046896835 @default.
• W1825599478 date "2014-10-10" @default.
• W1825599478 modified "2023-09-23" @default.
• W1825599478 title "Expression of DNA cytosine deaminase APOBEC3 proteins, a potential source for producing mutations, in gastric, colorectal and prostate cancers." @default.
• W1825599478 cites W1789875395 @default.
• W1825599478 cites W1966477735 @default.
• W1825599478 cites W1979946545 @default.
• W1825599478 cites W1980262173 @default.
• W1825599478 cites W1984236815 @default.
• W1825599478 cites W1997746246 @default.
• W1825599478 cites W1999207703 @default.
• W1825599478 cites W2013958019 @default.
• W1825599478 cites W2023568503 @default.
• W1825599478 cites W2034269086 @default.
• W1825599478 cites W2049930242 @default.
• W1825599478 cites W2072626324 @default.
• W1825599478 cites W2096283457 @default.
• W1825599478 cites W2100984579 @default.
• W1825599478 cites W2129136620 @default.
• W1825599478 cites W2144497460 @default.
• W1825599478 cites W2159607262 @default.
• W1825599478 doi "https://doi.org/10.1700/1636.17922" @default.
• W1825599478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25296601" @default.
• W1825599478 hasPublicationYear "2014" @default.
• W1825599478 type Work @default.
• W1825599478 sameAs 1825599478 @default.
• W1825599478 citedByCount "6" @default.
• W1825599478 countsByYear W18255994782015 @default.
• W1825599478 countsByYear W18255994782017 @default.
• W1825599478 countsByYear W18255994782018 @default.
• W1825599478 countsByYear W18255994782022 @default.
• W1825599478 countsByYear W18255994782023 @default.
• W1825599478 crossrefType "journal-article" @default.
• W1825599478 hasAuthorship W1825599478A5005078397 @default.
• W1825599478 hasAuthorship W1825599478A5015567806 @default.
• W1825599478 hasAuthorship W1825599478A5030743761 @default.
• W1825599478 hasAuthorship W1825599478A5046896835 @default.
• W1825599478 hasConcept C104317684 @default.
• W1825599478 hasConcept C111599444 @default.
• W1825599478 hasConcept C121608353 @default.
• W1825599478 hasConcept C126322002 @default.
• W1825599478 hasConcept C141231307 @default.
• W1825599478 hasConcept C142724271 @default.
• W1825599478 hasConcept C159654299 @default.
• W1825599478 hasConcept C203014093 @default.
• W1825599478 hasConcept C204232928 @default.
• W1825599478 hasConcept C2776162770 @default.
• W1825599478 hasConcept C2776235491 @default.
• W1825599478 hasConcept C2776985229 @default.
• W1825599478 hasConcept C2777748644 @default.
• W1825599478 hasConcept C2779013556 @default.
• W1825599478 hasConcept C2780192828 @default.
• W1825599478 hasConcept C501734568 @default.
• W1825599478 hasConcept C502942594 @default.
• W1825599478 hasConcept C526805850 @default.
• W1825599478 hasConcept C530470458 @default.
• W1825599478 hasConcept C54355233 @default.
• W1825599478 hasConcept C555283112 @default.
• W1825599478 hasConcept C71924100 @default.
• W1825599478 hasConcept C86803240 @default.
• W1825599478 hasConceptScore W1825599478C104317684 @default.
• W1825599478 hasConceptScore W1825599478C111599444 @default.
• W1825599478 hasConceptScore W1825599478C121608353 @default.
• W1825599478 hasConceptScore W1825599478C126322002 @default.
• W1825599478 hasConceptScore W1825599478C141231307 @default.
• W1825599478 hasConceptScore W1825599478C142724271 @default.
• W1825599478 hasConceptScore W1825599478C159654299 @default.
• W1825599478 hasConceptScore W1825599478C203014093 @default.
• W1825599478 hasConceptScore W1825599478C204232928 @default.
• W1825599478 hasConceptScore W1825599478C2776162770 @default.
• W1825599478 hasConceptScore W1825599478C2776235491 @default.
• W1825599478 hasConceptScore W1825599478C2776985229 @default.
• W1825599478 hasConceptScore W1825599478C2777748644 @default.
• W1825599478 hasConceptScore W1825599478C2779013556 @default.
• W1825599478 hasConceptScore W1825599478C2780192828 @default.
• W1825599478 hasConceptScore W1825599478C501734568 @default.
• W1825599478 hasConceptScore W1825599478C502942594 @default.
• W1825599478 hasConceptScore W1825599478C526805850 @default.
• W1825599478 hasConceptScore W1825599478C530470458 @default.
• W1825599478 hasConceptScore W1825599478C54355233 @default.
• W1825599478 hasConceptScore W1825599478C555283112 @default.
• W1825599478 hasConceptScore W1825599478C71924100 @default.
• W1825599478 hasConceptScore W1825599478C86803240 @default.
• W1825599478 hasIssue "4" @default.
• W1825599478 hasLocation W18255994781 @default.
• W1825599478 hasOpenAccess W1825599478 @default.
• W1825599478 hasPrimaryLocation W18255994781 @default.
• W1825599478 hasRelatedWork W2017009483 @default.
• W1825599478 hasRelatedWork W2106003470 @default.
• W1825599478 hasRelatedWork W2350150832 @default.
• W1825599478 hasRelatedWork W2353465412 @default.
• W1825599478 hasRelatedWork W2383887597 @default.
• W1825599478 hasRelatedWork W2401442197 @default.

• next