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• W1826315897 endingPage "1019" @default.
• W1826315897 startingPage "1009" @default.
• W1826315897 abstract "MicroRNAs (miRNAs) are 19 – 24 nucleotide noncoding RNAs that regulate the translation and degradation of target mRNAs and are extensively involved in human cancers. One unexpected conclusion of the profiling and functional studies in tumourigenesis is that some miRNAs behave in cancer cells in a dual mode, resembling the ‘Dr Jekyll and Mr Hyde’ story, which centers on a conception of humanity as dual in nature. The authors and others have found that onco-miRNAs and suppressor-miRNAs can represent two different looks of the same gene, behaving as oncogenes or tumour suppressors depending on tissue type and specific targets. In this review, the authors analyse the regulatory mechanisms of the main miRNA genes involved in human tumourigenesis." @default.
• W1826315897 created "2016-06-24" @default.
• W1826315897 creator A5004315502 @default.
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• W1826315897 creator A5044003367 @default.
• W1826315897 creator A5079980788 @default.
• W1826315897 creator A5087506952 @default.
• W1826315897 date "2007-07-01" @default.
• W1826315897 modified "2023-10-03" @default.
• W1826315897 title "Regulatory mechanisms of microRNAs involvement in cancer" @default.
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• W1826315897 doi "https://doi.org/10.1517/14712598.7.7.1009" @default.

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