FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1826374502> ?p ?o ?g. }

• W1826374502 endingPage "3645" @default.
• W1826374502 startingPage "3635" @default.
• W1826374502 abstract "Recent work has shown that many promoters recognized by eucaryotic RNA polymerase II contain essential sequences located downstream of the transcriptional initiation site. We show here that the activity of a promoter element centered 28 base pairs downstream of the simian virus 40 major late initiation site appears to be mediated by a DNA-binding protein, which was isolated by affinity chromatography from HeLa cell nuclear extracts. In the absence of the other components of the transcriptional machinery, the protein bound specifically but weakly to its recognition sequence, with a Kd of approximately 10(-8) M. Analysis of kinetic data showed that mutation of the downstream element decreased the number of functional preinitiation complexes assembled at the promoter without significantly altering the time required for half the complexes to assemble. This suggests that in the absence of the downstream activating protein, preinitiation complexes are at least partially assembled but are not transcriptionally competent." @default.
• W1826374502 created "2016-06-24" @default.
• W1826374502 creator A5051909812 @default.
• W1826374502 creator A5074438352 @default.
• W1826374502 date "1990-07-01" @default.
• W1826374502 modified "2023-10-16" @default.
• W1826374502 title "A downstream-element-binding factor facilitates assembly of a functional preinitiation complex at the simian virus 40 major late promoter." @default.
• W1826374502 cites W1486767369 @default.
• W1826374502 cites W1487821532 @default.
• W1826374502 cites W1488696100 @default.
• W1826374502 cites W1490501591 @default.
• W1826374502 cites W1490745525 @default.
• W1826374502 cites W1491615231 @default.
• W1826374502 cites W1527092816 @default.
• W1826374502 cites W1546018786 @default.
• W1826374502 cites W1550856848 @default.
• W1826374502 cites W1558516755 @default.
• W1826374502 cites W1558941855 @default.
• W1826374502 cites W1568843108 @default.
• W1826374502 cites W1593629400 @default.
• W1826374502 cites W1595727495 @default.
• W1826374502 cites W1596038925 @default.
• W1826374502 cites W1617139585 @default.
• W1826374502 cites W1627615914 @default.
• W1826374502 cites W1687511301 @default.
• W1826374502 cites W1689599151 @default.
• W1826374502 cites W1716848917 @default.
• W1826374502 cites W1848762606 @default.
• W1826374502 cites W1855074355 @default.
• W1826374502 cites W1868416771 @default.
• W1826374502 cites W1871801806 @default.
• W1826374502 cites W1905356657 @default.
• W1826374502 cites W1925299994 @default.
• W1826374502 cites W1965267927 @default.
• W1826374502 cites W1967767330 @default.
• W1826374502 cites W1973381207 @default.
• W1826374502 cites W1975987535 @default.
• W1826374502 cites W1980014349 @default.
• W1826374502 cites W1989080074 @default.
• W1826374502 cites W1993644340 @default.
• W1826374502 cites W1996251138 @default.
• W1826374502 cites W1998926449 @default.
• W1826374502 cites W2004563262 @default.
• W1826374502 cites W2010049199 @default.
• W1826374502 cites W2015502095 @default.
• W1826374502 cites W2018796983 @default.
• W1826374502 cites W2039201183 @default.
• W1826374502 cites W2040193953 @default.
• W1826374502 cites W2052357638 @default.
• W1826374502 cites W2053956877 @default.
• W1826374502 cites W2067722023 @default.
• W1826374502 cites W2071802835 @default.
• W1826374502 cites W2072528655 @default.
• W1826374502 cites W2074351361 @default.
• W1826374502 cites W2084748297 @default.
• W1826374502 cites W2089843624 @default.
• W1826374502 cites W2093428365 @default.
• W1826374502 cites W2095190491 @default.
• W1826374502 cites W2107624922 @default.
• W1826374502 cites W2117687169 @default.
• W1826374502 cites W2125724889 @default.
• W1826374502 cites W2128635872 @default.
• W1826374502 cites W2134078619 @default.
• W1826374502 cites W2134305122 @default.
• W1826374502 cites W2147224696 @default.
• W1826374502 cites W2148633495 @default.
• W1826374502 cites W2148665498 @default.
• W1826374502 cites W958315937 @default.
• W1826374502 doi "https://doi.org/10.1128/mcb.10.7.3635" @default.
• W1826374502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/360800" @default.
• W1826374502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2162478" @default.
• W1826374502 hasPublicationYear "1990" @default.
• W1826374502 type Work @default.
• W1826374502 sameAs 1826374502 @default.
• W1826374502 citedByCount "34" @default.
• W1826374502 crossrefType "journal-article" @default.
• W1826374502 hasAuthorship W1826374502A5051909812 @default.
• W1826374502 hasAuthorship W1826374502A5074438352 @default.
• W1826374502 hasBestOaLocation W18263745021 @default.
• W1826374502 hasConcept C101762097 @default.
• W1826374502 hasConcept C104317684 @default.
• W1826374502 hasConcept C107824862 @default.
• W1826374502 hasConcept C138885662 @default.
• W1826374502 hasConcept C150194340 @default.
• W1826374502 hasConcept C153911025 @default.
• W1826374502 hasConcept C156951783 @default.
• W1826374502 hasConcept C179926584 @default.
• W1826374502 hasConcept C188740287 @default.
• W1826374502 hasConcept C41895202 @default.
• W1826374502 hasConcept C54355233 @default.
• W1826374502 hasConcept C86803240 @default.
• W1826374502 hasConcept C95444343 @default.
• W1826374502 hasConceptScore W1826374502C101762097 @default.
• W1826374502 hasConceptScore W1826374502C104317684 @default.
• W1826374502 hasConceptScore W1826374502C107824862 @default.
• W1826374502 hasConceptScore W1826374502C138885662 @default.
• W1826374502 hasConceptScore W1826374502C150194340 @default.
• W1826374502 hasConceptScore W1826374502C153911025 @default.

• next