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- W1826645893 abstract "A series of functionalized 3-fluoro-2,3-dihydro-4H-pyran derivatives were efficiently synthesized from ethyl 2-fluoroacetoacetate 1, malononitrile 2 and aromatic aldehydes 3 via one-pot, multi-component reactions catalyzed by NaOH. The solvent ethanol played dual roles as both reactant and reaction medium, resulting in the further occurrence of intramolecular cyclization to afford cyclic products 4. The structures of product 4 were determined by spectral methods and X-ray diffraction analysis. A possible reaction mechanism for the formation of 4 was presented on the basis of two supporting experiments." @default.
- W1826645893 created "2016-06-24" @default.
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- W1826645893 date "2015-08-01" @default.
- W1826645893 modified "2023-10-13" @default.
- W1826645893 title "Convenient one-pot synthesis of monofluorinated functionalized 4-H-pyran derivatives via multi-component reactions" @default.
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- W1826645893 doi "https://doi.org/10.1016/j.jfluchem.2015.05.008" @default.
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