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• W1827217512 abstract "Abstract Context.—Medial calcification of muscular arteries is known as Monckeberg sclerosis (MS). Although this was first described in 1903, disagreement persists over its precise histologic appearance. Some, including Monckeberg, have written that the media alone are calcified, whereas others maintain that both the media and internal elastic lamina (IEL) are involved. Since vascular calcification is of great interest to investigators and clinicians, defined criteria for classifying calcified arterial lesions are important. Objective.—To clarify the histologic definition of MS with regard to calcification of the IEL. Design.—We reviewed slides from 14 incisional and excisional surgical biopsies and autopsy specimens containing arteries with previously diagnosed MS. We looked specifically for medial and IEL calcification and used von Kossa, alizarin red, and trichrome/elastic stains to confirm our findings. We also performed a literature search on the histologic appearance of MS. Results.—Both medial and ..." @default.
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• W1827217512 date "2008-01-01" @default.
• W1827217512 modified "2023-10-11" @default.
• W1827217512 title "Monckeberg sclerosis revisited: a clarification of the histologic definition of Monckeberg sclerosis." @default.
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• W1827217512 doi "https://doi.org/10.1043/1543-2165(2008)132[43:msraco]2.0.co;2" @default.
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