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- W1827391868 abstract "Publisher Summary This chapter provides an overview of the state of the science for pesticide biomonitoring research. It presents the fundamental concepts and primary uses of biomonitoring and then highlights the major criteria required for the selection and use of biomarkers in population-based exposure studies. It also focuses on factors that affect the use and interpretation of biomarkers of exposure for current-use pesticides. Biomonitoring is an important tool that can be used to evaluate human exposure to pesticides by measuring the levels of pesticides, pesticide metabolites, or altered biological structures or functions in biological specimens or tissues. These measurements in biological media, referred to as biomarkers, reflect human exposure to pesticides through all relevant routes and can therefore be used to monitor aggregate and cumulative exposures. The complexity of aggregate and cumulative pesticide exposures often obscures the linkages between exposure measurements and potential human health effects. Therefore, biomonitoring offers a means to clarify these critical relationships. However, careful interpretation of biomonitoring data is necessary to accurately assess human exposure to pesticides and the associated human health risks. One of the biggest challenges facing pesticide biomonitoring research is the interpretation of measurements of nonpersistent current-use pesticides in samples of human urine. Urinary measurements of nonpersistent pesticide biomarkers are difficult to interpret in terms of exposure and dose because of their highly variable nature and other influential factors." @default.
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- W1827391868 date "2010-01-01" @default.
- W1827391868 modified "2023-09-29" @default.
- W1827391868 title "Biomonitoring" @default.
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- W1827391868 doi "https://doi.org/10.1016/b978-0-12-374367-1.00045-8" @default.
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