Matches in SemOpenAlex for { <https://semopenalex.org/work/W1828379848> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1828379848 endingPage "484" @default.
- W1828379848 startingPage "481" @default.
- W1828379848 abstract "Abstract Purpose To date, there is a wide range of methods in use to assess endothelial function, each with its own advantages and limitations. Here, we tested hypothesis that real‐time RT‐PCR threshold value (Ct), which is reflective of mRNA level, for Glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) from whole blood is indicative of endothelial function in humans. Materials and Methods To assess vascular function, we measured baseline skin perfusion, postocclusion reactive hyperemia (PORH), and brachial artery flow‐mediated dilatation (FMD) and tested for a possible correlation between vascular responses and blood GAPDH real‐time RT‐PCR Ct value in 75 healthy volunteers. Results Tests known to measure, at least in part, endothelial function such as baseline skin perfusion, the 2‐minute recovery PORH, and FMD exhibited significant positive correlations with blood GAPDH Ct values. In contrast, there was no significant correlation between Ct values for blood GAPDH and peak PORH, an endothelium‐independent parameter. Conclusions Based on these findings, we report that GAPDH mRNA level in the blood correlates with vascular function in healthy subjects. This suggests that GAPDH mRNA level could be a potential biomarker of vascular endothelial function." @default.
- W1828379848 created "2016-06-24" @default.
- W1828379848 creator A5005135256 @default.
- W1828379848 creator A5020533673 @default.
- W1828379848 creator A5022356679 @default.
- W1828379848 creator A5024998198 @default.
- W1828379848 date "2013-04-19" @default.
- W1828379848 modified "2023-10-17" @default.
- W1828379848 title "Real-Time RT-PCR Ct Values for Blood GAPDH Correlate with Measures of Vascular Endothelial Function in Humans" @default.
- W1828379848 cites W1537911503 @default.
- W1828379848 cites W1555489744 @default.
- W1828379848 cites W1976205937 @default.
- W1828379848 cites W2037752735 @default.
- W1828379848 cites W2038213115 @default.
- W1828379848 cites W2066374288 @default.
- W1828379848 cites W2103712309 @default.
- W1828379848 cites W2130050966 @default.
- W1828379848 cites W2136198301 @default.
- W1828379848 cites W2154081746 @default.
- W1828379848 doi "https://doi.org/10.1111/cts.12053" @default.
- W1828379848 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5350972" @default.
- W1828379848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24330693" @default.
- W1828379848 hasPublicationYear "2013" @default.
- W1828379848 type Work @default.
- W1828379848 sameAs 1828379848 @default.
- W1828379848 citedByCount "4" @default.
- W1828379848 countsByYear W18283798482014 @default.
- W1828379848 countsByYear W18283798482015 @default.
- W1828379848 countsByYear W18283798482019 @default.
- W1828379848 countsByYear W18283798482022 @default.
- W1828379848 crossrefType "journal-article" @default.
- W1828379848 hasAuthorship W1828379848A5005135256 @default.
- W1828379848 hasAuthorship W1828379848A5020533673 @default.
- W1828379848 hasAuthorship W1828379848A5022356679 @default.
- W1828379848 hasAuthorship W1828379848A5024998198 @default.
- W1828379848 hasBestOaLocation W18283798482 @default.
- W1828379848 hasConcept C104317684 @default.
- W1828379848 hasConcept C126322002 @default.
- W1828379848 hasConcept C134792803 @default.
- W1828379848 hasConcept C142724271 @default.
- W1828379848 hasConcept C146957229 @default.
- W1828379848 hasConcept C158846371 @default.
- W1828379848 hasConcept C164705383 @default.
- W1828379848 hasConcept C181199279 @default.
- W1828379848 hasConcept C2776317432 @default.
- W1828379848 hasConcept C2776992346 @default.
- W1828379848 hasConcept C2777604165 @default.
- W1828379848 hasConcept C2781197716 @default.
- W1828379848 hasConcept C3019128504 @default.
- W1828379848 hasConcept C48023723 @default.
- W1828379848 hasConcept C55493867 @default.
- W1828379848 hasConcept C71924100 @default.
- W1828379848 hasConcept C84393581 @default.
- W1828379848 hasConcept C86803240 @default.
- W1828379848 hasConceptScore W1828379848C104317684 @default.
- W1828379848 hasConceptScore W1828379848C126322002 @default.
- W1828379848 hasConceptScore W1828379848C134792803 @default.
- W1828379848 hasConceptScore W1828379848C142724271 @default.
- W1828379848 hasConceptScore W1828379848C146957229 @default.
- W1828379848 hasConceptScore W1828379848C158846371 @default.
- W1828379848 hasConceptScore W1828379848C164705383 @default.
- W1828379848 hasConceptScore W1828379848C181199279 @default.
- W1828379848 hasConceptScore W1828379848C2776317432 @default.
- W1828379848 hasConceptScore W1828379848C2776992346 @default.
- W1828379848 hasConceptScore W1828379848C2777604165 @default.
- W1828379848 hasConceptScore W1828379848C2781197716 @default.
- W1828379848 hasConceptScore W1828379848C3019128504 @default.
- W1828379848 hasConceptScore W1828379848C48023723 @default.
- W1828379848 hasConceptScore W1828379848C55493867 @default.
- W1828379848 hasConceptScore W1828379848C71924100 @default.
- W1828379848 hasConceptScore W1828379848C84393581 @default.
- W1828379848 hasConceptScore W1828379848C86803240 @default.
- W1828379848 hasIssue "6" @default.
- W1828379848 hasLocation W18283798481 @default.
- W1828379848 hasLocation W18283798482 @default.
- W1828379848 hasLocation W18283798483 @default.
- W1828379848 hasLocation W18283798484 @default.
- W1828379848 hasOpenAccess W1828379848 @default.
- W1828379848 hasPrimaryLocation W18283798481 @default.
- W1828379848 hasRelatedWork W2012104272 @default.
- W1828379848 hasRelatedWork W2348397476 @default.
- W1828379848 hasRelatedWork W2360248352 @default.
- W1828379848 hasRelatedWork W2369904190 @default.
- W1828379848 hasRelatedWork W2383402891 @default.
- W1828379848 hasRelatedWork W2401399753 @default.
- W1828379848 hasRelatedWork W2408550616 @default.
- W1828379848 hasRelatedWork W2411437731 @default.
- W1828379848 hasRelatedWork W2618495366 @default.
- W1828379848 hasRelatedWork W2774794453 @default.
- W1828379848 hasVolume "6" @default.
- W1828379848 isParatext "false" @default.
- W1828379848 isRetracted "false" @default.
- W1828379848 magId "1828379848" @default.
- W1828379848 workType "article" @default.