FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1828538861> ?p ?o ?g. }

• W1828538861 endingPage "158" @default.
• W1828538861 startingPage "152" @default.
• W1828538861 abstract "Neoadjuvant chemoradiotherapy (nCRT) improves survival in esophageal cancer (EC) patients, but the response to treatment is heterogeneous and little is known regarding prognostic and predictive markers in these patients. CD44, SOX2 and SHH have been implicated in resistance to CRT, possibly through an association with a cancer stem cell phenotype.101 EC patients treated with nCRT and surgery were included. Sufficient pre-treatment biopsy material was present in 71 patients, of which 53 patients were non-complete responders on nCRT (nCR). Protein expression was examined using immunohistochemistry (IHC). Prognostic factors were determined using Cox regression analysis for disease free survival (DFS) and cause specific survival (CSS) in the complete cohort, the pre-treatment biopsies group and post-treatment nCR group.Low CD44 expression in the nCR group was an independent prognostic factor for both DFS and CSS (DFS HR 2.81, p=0.002 and CSS HR 3.48, p=0.002). Absent SOX2 expression in pretreatment biopsies was related to systemic recurrence (p=0.029) while low SHH in pretreatment biopsies was an independent prognostic factor for a poor DFS (HR 2.27, p=0.036). No relation between marker expression and response to nCRT was observed.Low expression of CD44 and SHH are associated with a poor survival outcome in EC patients treated with nCRT." @default.
• W1828538861 created "2016-06-24" @default.
• W1828538861 creator A5011298606 @default.
• W1828538861 creator A5013384569 @default.
• W1828538861 creator A5024840057 @default.
• W1828538861 creator A5042275454 @default.
• W1828538861 creator A5061261749 @default.
• W1828538861 creator A5064417583 @default.
• W1828538861 creator A5070456340 @default.
• W1828538861 creator A5074534013 @default.
• W1828538861 creator A5075174309 @default.
• W1828538861 creator A5078429982 @default.
• W1828538861 creator A5085160266 @default.
• W1828538861 creator A5060519519 @default.
• W1828538861 date "2015-10-01" @default.
• W1828538861 modified "2023-10-01" @default.
• W1828538861 title "CD44, SHH and SOX2 as novel biomarkers in esophageal cancer patients treated with neoadjuvant chemoradiotherapy" @default.
• W1828538861 cites W1940086102 @default.
• W1828538861 cites W1967585707 @default.
• W1828538861 cites W1970251135 @default.
• W1828538861 cites W1977468182 @default.
• W1828538861 cites W1981053693 @default.
• W1828538861 cites W1989313612 @default.
• W1828538861 cites W2012801703 @default.
• W1828538861 cites W2016251600 @default.
• W1828538861 cites W2016416086 @default.
• W1828538861 cites W2022168604 @default.
• W1828538861 cites W2036870885 @default.
• W1828538861 cites W2042328084 @default.
• W1828538861 cites W2060795278 @default.
• W1828538861 cites W2061226390 @default.
• W1828538861 cites W2081447858 @default.
• W1828538861 cites W2098076875 @default.
• W1828538861 cites W2108981351 @default.
• W1828538861 cites W2109207338 @default.
• W1828538861 cites W2116069291 @default.
• W1828538861 cites W2129134396 @default.
• W1828538861 cites W2131779232 @default.
• W1828538861 cites W2138576529 @default.
• W1828538861 cites W2140350596 @default.
• W1828538861 cites W2140490644 @default.
• W1828538861 cites W2144715657 @default.
• W1828538861 cites W2152627545 @default.
• W1828538861 cites W2154444715 @default.
• W1828538861 cites W2159405948 @default.
• W1828538861 doi "https://doi.org/10.1016/j.radonc.2015.08.031" @default.
• W1828538861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26364884" @default.
• W1828538861 hasPublicationYear "2015" @default.
• W1828538861 type Work @default.
• W1828538861 sameAs 1828538861 @default.
• W1828538861 citedByCount "19" @default.
• W1828538861 countsByYear W18285388612016 @default.
• W1828538861 countsByYear W18285388612017 @default.
• W1828538861 countsByYear W18285388612018 @default.
• W1828538861 countsByYear W18285388612019 @default.
• W1828538861 countsByYear W18285388612020 @default.
• W1828538861 countsByYear W18285388612021 @default.
• W1828538861 countsByYear W18285388612023 @default.
• W1828538861 crossrefType "journal-article" @default.
• W1828538861 hasAuthorship W1828538861A5011298606 @default.
• W1828538861 hasAuthorship W1828538861A5013384569 @default.
• W1828538861 hasAuthorship W1828538861A5024840057 @default.
• W1828538861 hasAuthorship W1828538861A5042275454 @default.
• W1828538861 hasAuthorship W1828538861A5060519519 @default.
• W1828538861 hasAuthorship W1828538861A5061261749 @default.
• W1828538861 hasAuthorship W1828538861A5064417583 @default.
• W1828538861 hasAuthorship W1828538861A5070456340 @default.
• W1828538861 hasAuthorship W1828538861A5074534013 @default.
• W1828538861 hasAuthorship W1828538861A5075174309 @default.
• W1828538861 hasAuthorship W1828538861A5078429982 @default.
• W1828538861 hasAuthorship W1828538861A5085160266 @default.
• W1828538861 hasBestOaLocation W18285388612 @default.
• W1828538861 hasConcept C121608353 @default.
• W1828538861 hasConcept C126322002 @default.
• W1828538861 hasConcept C142724271 @default.
• W1828538861 hasConcept C143998085 @default.
• W1828538861 hasConcept C1491633281 @default.
• W1828538861 hasConcept C204232928 @default.
• W1828538861 hasConcept C2775934546 @default.
• W1828538861 hasConcept C2778292576 @default.
• W1828538861 hasConcept C2778424827 @default.
• W1828538861 hasConcept C2779742542 @default.
• W1828538861 hasConcept C2780932548 @default.
• W1828538861 hasConcept C50382708 @default.
• W1828538861 hasConcept C530470458 @default.
• W1828538861 hasConcept C54355233 @default.
• W1828538861 hasConcept C71924100 @default.
• W1828538861 hasConcept C86803240 @default.
• W1828538861 hasConcept C90924648 @default.
• W1828538861 hasConceptScore W1828538861C121608353 @default.
• W1828538861 hasConceptScore W1828538861C126322002 @default.
• W1828538861 hasConceptScore W1828538861C142724271 @default.
• W1828538861 hasConceptScore W1828538861C143998085 @default.
• W1828538861 hasConceptScore W1828538861C1491633281 @default.
• W1828538861 hasConceptScore W1828538861C204232928 @default.
• W1828538861 hasConceptScore W1828538861C2775934546 @default.
• W1828538861 hasConceptScore W1828538861C2778292576 @default.
• W1828538861 hasConceptScore W1828538861C2778424827 @default.

• next