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• W1830264788 startingPage "287" @default.
• W1830264788 abstract "The association between human papillomavirus (HPV) and esophageal squamous cell carcinoma (ESCC) has been recognized for over three decades. Recently, multiple meta-analyses have drawn upon existing literature to assess the strength of the HPV-ESCC linkage. Here, we review these analyses and attempt to provide a clinically-relevant overview of HPV infection in ESCC. HPV-ESCC detection rates are highly variable across studies. Geographic location likely accounts for a majority of the variation in HPV prevalence, with high-incidence regions including Asia reporting significantly higher HPV-ESCC infection rates compared with low-incidence regions such as Europe, North America, and Oceania. Based on our examination of existing data, the current literature does not support the notion that HPV is a prominent carcinogen in ESCC. We conclude that there is no basis to change the current clinical approach to ESCC patients with respect to tumor HPV status." @default.
• W1830264788 created "2016-06-24" @default.
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• W1830264788 date "2015-06-01" @default.
• W1830264788 modified "2023-09-29" @default.
• W1830264788 title "Human papillomavirus tumor infection in esophageal squamous cell carcinoma." @default.
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• W1830264788 doi "https://doi.org/10.3978/j.issn.2078-6891.2015.001" @default.
• W1830264788 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4397257" @default.
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